Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | zinc finger protein 598 | 0.0062 | 0.6795 | 0.988 |
Loa Loa (eye worm) | brix domain-containing protein | 0.0062 | 0.6877 | 0.6877 |
Brugia malayi | Brix domain containing protein | 0.0062 | 0.6877 | 0.6453 |
Toxoplasma gondii | brix domain-containing protein | 0.0062 | 0.6877 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1195 | 0.1195 |
Trichomonas vaginalis | ssf, putative | 0.0062 | 0.6877 | 0.5 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0077 | 1 | 1 |
Giardia lamblia | Peter pan protein | 0.0062 | 0.6877 | 0.5 |
Trypanosoma brucei | brix domain containing protein, putative | 0.0062 | 0.6877 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1195 | 0.1195 |
Onchocerca volvulus | 0.0077 | 1 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0077 | 1 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Trypanosoma cruzi | peter pan protein, putative | 0.0062 | 0.6877 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Leishmania major | peter pan protein, putative | 0.0062 | 0.6877 | 0.5 |
Entamoeba histolytica | brix domain containing protein | 0.0062 | 0.6877 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Echinococcus multilocularis | zinc finger protein 598 | 0.0062 | 0.6795 | 0.988 |
Schistosoma mansoni | peter pan-related | 0.0062 | 0.6877 | 0.6453 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Echinococcus multilocularis | peter pan | 0.0062 | 0.6877 | 1 |
Schistosoma mansoni | peter pan-related | 0.0062 | 0.6877 | 0.6453 |
Trypanosoma cruzi | peter pan protein, putative | 0.0062 | 0.6877 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1195 | 0.1195 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Echinococcus granulosus | peter pan | 0.0062 | 0.6877 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Plasmodium vivax | hypothetical protein, conserved | 0.0062 | 0.6877 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Plasmodium falciparum | BRIX domain, putative | 0.0062 | 0.6877 | 0.5 |
Onchocerca volvulus | Peter pan protein homolog | 0.0062 | 0.6877 | 0.6453 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0036 | 0.1195 | 0.1738 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.