Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0083 | 0.0236 | 0.0236 |
Schistosoma mansoni | adapter molecule crk | 0.007 | 0.0142 | 0.0142 |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1379 | 0.1379 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0083 | 0.0236 | 0.0236 |
Schistosoma mansoni | tyrosine kinase | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0238 | 0.1379 | 0.1379 |
Schistosoma mansoni | nck2/grb4 | 0.007 | 0.0142 | 0.0142 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1409 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0238 | 0.1379 | 0.1379 |
Echinococcus granulosus | c src tyrosine kinase | 0.0083 | 0.0236 | 0.0236 |
Echinococcus granulosus | carboxylesterase 5A | 0.1409 | 1 | 1 |
Echinococcus granulosus | NCK adaptor protein | 0.007 | 0.0142 | 0.0142 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0083 | 0.0236 | 0.0236 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0238 | 0.1379 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0083 | 0.0236 | 0.0236 |
Onchocerca volvulus | 0.0238 | 0.1379 | 1 | |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0083 | 0.0236 | 0.0236 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0238 | 0.1379 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0238 | 0.1379 | 0.1379 |
Loa Loa (eye worm) | hypothetical protein | 0.1409 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Schistosoma mansoni | acetylcholinesterase | 0.0238 | 0.1379 | 0.1379 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0083 | 0.0236 | 0.0236 |
Schistosoma mansoni | gliotactin | 0.0238 | 0.1379 | 0.1379 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.007 | 0.0142 | 0.0142 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.007 | 0.0142 | 0.0142 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0238 | 0.1379 | 0.1379 |
Loa Loa (eye worm) | carboxylesterase | 0.0238 | 0.1379 | 0.1379 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.007 | 0.0142 | 0.0142 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.007 | 0.0142 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.1409 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1409 | 1 | 1 |
Brugia malayi | SRC-1 | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0238 | 0.1379 | 0.1379 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Brugia malayi | Carboxylesterase family protein | 0.1409 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0083 | 0.0236 | 0.0236 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0238 | 0.1379 | 0.1379 |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1379 | 0.1379 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0083 | 0.0236 | 0.0236 |
Onchocerca volvulus | 0.0238 | 0.1379 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0238 | 0.1379 | 0.1379 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0238 | 0.1379 | 0.5 |
Brugia malayi | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0083 | 0.0236 | 0.0236 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0083 | 0.0236 | 0.0236 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0238 | 0.1379 | 0.1379 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0238 | 0.1379 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0083 | 0.0236 | 0.0236 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0083 | 0.0236 | 0.0236 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0083 | 0.0236 | 0.0236 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | acetylcholinesterase | 0.1409 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0083 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1409 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0083 | 0.0236 | 0.0236 |
Brugia malayi | Variant SH3 domain containing protein | 0.007 | 0.0142 | 0.0142 |
Schistosoma mansoni | tyrosine kinase | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | NCK adaptor protein | 0.007 | 0.0142 | 0.0142 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0238 | 0.1379 | 0.1379 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.007 | 0.0142 | 0.0142 |
Loa Loa (eye worm) | SRC-1 | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | acetylcholinesterase | 0.1409 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0083 | 0.0236 | 0.0236 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0238 | 0.1379 | 0.1379 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0083 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.007 | 0.0142 | 0.0142 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.007 | 0.0142 | 0.0142 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0238 | 0.1379 | 0.5 |
Onchocerca volvulus | 0.0238 | 0.1379 | 1 | |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0083 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0142 | 0.0142 |
Brugia malayi | Variant SH3 domain containing protein | 0.007 | 0.0142 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0083 | 0.0236 | 0.0236 |
Echinococcus multilocularis | neuroligin | 0.0238 | 0.1379 | 0.1379 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0238 | 0.1379 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1379 | 0.1379 |
Loa Loa (eye worm) | carboxylesterase | 0.1409 | 1 | 1 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.007 | 0.0142 | 0.0142 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0238 | 0.1379 | 0.1379 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1379 | 0.1379 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0083 | 0.0236 | 0.0236 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0238 | 0.1379 | 0.1379 |
Echinococcus granulosus | acetylcholinesterase | 0.1409 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0238 | 0.1379 | 0.1379 |
Onchocerca volvulus | 0.0238 | 0.1379 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1409 | 1 | 1 |
Onchocerca volvulus | 0.0238 | 0.1379 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1379 | 0.1379 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0083 | 0.0236 | 0.0236 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.