Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0052 | 0.33 | 0.3019 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.0052 | 0.33 | 0.4528 |
Giardia lamblia | Kinase, CMGC GSK | 0.0052 | 0.33 | 0.7121 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.33 | 0.7121 |
Entamoeba histolytica | protein kinase, putative | 0.0052 | 0.33 | 0.7121 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.3385 | 0.3107 |
Echinococcus granulosus | glutaminyl tRNA synthetase | 0.0091 | 0.6801 | 1 |
Trichomonas vaginalis | glutaminyl-tRNA synthetase, putative | 0.0065 | 0.4472 | 1 |
Schistosoma mansoni | glutaminyl-tRNA synthetase (glutamine--tRNA ligase) (glnrs) | 0.0091 | 0.6801 | 1 |
Echinococcus multilocularis | glutaminyl tRNA synthetase | 0.0091 | 0.6801 | 1 |
Leishmania major | glutaminyl-tRNA synthetase, putative | 0.0029 | 0.1272 | 0.3 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0052 | 0.33 | 1 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0052 | 0.33 | 1 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0052 | 0.33 | 1 |
Echinococcus granulosus | protein kinase shaggy | 0.0052 | 0.33 | 0.4528 |
Trypanosoma cruzi | asparaginyl-tRNA synthetase, putative | 0.0036 | 0.1932 | 0.5275 |
Loa Loa (eye worm) | glutaminyl-tRNA synthetase | 0.0128 | 1 | 1 |
Plasmodium falciparum | glutamine--tRNA ligase, putative | 0.0029 | 0.1272 | 0.3 |
Giardia lamblia | Kinase, CMGC GSK | 0.0052 | 0.33 | 0.7121 |
Trypanosoma brucei | protein kinase, putative | 0.0052 | 0.33 | 1 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.0052 | 0.33 | 0.4528 |
Toxoplasma gondii | glutaminyl-tRNA synthetase (GlnRS) | 0.0029 | 0.1272 | 0.3855 |
Trypanosoma cruzi | glutaminyl-tRNA synthetase, putative | 0.0029 | 0.1272 | 0.3 |
Giardia lamblia | Glutaminyl-tRNA synthetase | 0.0065 | 0.4472 | 1 |
Echinococcus multilocularis | protein kinase shaggy | 0.0052 | 0.33 | 0.4528 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0052 | 0.33 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0052 | 0.33 | 0.7121 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.0052 | 0.33 | 0.4528 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0052 | 0.33 | 0.7121 |
Trypanosoma brucei | glutaminyl-tRNA synthetase, putative | 0.0029 | 0.1272 | 0.3 |
Trypanosoma brucei | asparaginyl-tRNA synthetase, putative | 0.0036 | 0.1932 | 0.5275 |
Onchocerca volvulus | 0.0052 | 0.33 | 1 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.33 | 0.7121 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0052 | 0.33 | 1 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0052 | 0.33 | 0.3019 |
Leishmania major | asparaginyl-tRNA synthetase, putative | 0.0036 | 0.1932 | 0.5275 |
Brugia malayi | intracellular kinase | 0.0052 | 0.33 | 0.3019 |
Entamoeba histolytica | glutaminyl-tRNA synthetase, putative | 0.0065 | 0.4472 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.