Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1271 | 0.2333 | 0.2785 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3171 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.108 | 0.1564 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Leishmania major | cathepsin L-like protease | 0.1271 | 0.2333 | 0.0911 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Onchocerca volvulus | 0.1271 | 0.2333 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.1271 | 0.2333 | 0.2785 |
Entamoeba histolytica | cysteine protease, putative | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.108 | 0.1564 | 0.144 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1271 | 0.2333 | 0.3615 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1271 | 0.2333 | 0.3615 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1271 | 0.2333 | 0.3615 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.2777 | 0.841 | 0.841 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.108 | 0.1564 | 0.2424 |
Onchocerca volvulus | Cathepsin L homolog | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0876 | 0.0742 | 0.115 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0876 | 0.0742 | 0.3182 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2292 | 0.6453 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1271 | 0.2333 | 0.0911 |
Plasmodium vivax | vivapain-2 | 0.1271 | 0.2333 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1271 | 0.2333 | 0.2785 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2292 | 0.6453 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1271 | 0.2333 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1271 | 0.2333 | 0.2785 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1271 | 0.2333 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1271 | 0.2333 | 0.3615 |
Brugia malayi | Cathepsin L-like precursor | 0.1271 | 0.2333 | 0.3615 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.108 | 0.1564 | 0.1564 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1271 | 0.2333 | 0.3615 |
Onchocerca volvulus | 0.1271 | 0.2333 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0876 | 0.0742 | 0.3182 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1271 | 0.2333 | 0.3615 |
Leishmania major | cathepsin L-like protease | 0.1271 | 0.2333 | 0.0911 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Onchocerca volvulus | 0.1271 | 0.2333 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.108 | 0.1564 | 0.6707 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2292 | 0.6453 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0876 | 0.0742 | 0.3182 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.2199 | 0.6077 | 0.6077 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Echinococcus granulosus | cathepsin b | 0.2292 | 0.6453 | 1 |
Plasmodium vivax | vivapain-2 | 0.1271 | 0.2333 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0876 | 0.0742 | 0.115 |
Leishmania major | cathepsin L-like protease | 0.1271 | 0.2333 | 0.0911 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1271 | 0.2333 | 0.3615 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Leishmania major | cathepsin L-like protease | 0.1271 | 0.2333 | 0.0911 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1271 | 0.2333 | 0.3615 |
Onchocerca volvulus | 0.1271 | 0.2333 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.108 | 0.1564 | 0.1564 |
Toxoplasma gondii | cathepsin CPL | 0.1271 | 0.2333 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2292 | 0.6453 | 0.6453 |
Brugia malayi | Cathepsin L-like precursor | 0.1271 | 0.2333 | 0.3615 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1271 | 0.2333 | 0.3615 |
Leishmania major | cathepsin L-like protease | 0.3171 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.1271 | 0.2333 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2292 | 0.6453 | 1 |
Onchocerca volvulus | 0.1271 | 0.2333 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1271 | 0.2333 | 0.3615 |
Onchocerca volvulus | Cathepsin L homolog | 0.1271 | 0.2333 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.108 | 0.1564 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1271 | 0.2333 | 0.2333 |
Giardia lamblia | Cathepsin B precursor | 0.108 | 0.1564 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.1271 | 0.2333 | 0.2785 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Echinococcus granulosus | cathepsin b | 0.2292 | 0.6453 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0876 | 0.0742 | 0.115 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Onchocerca volvulus | 0.1271 | 0.2333 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.1271 | 0.2333 | 0.3615 |
Leishmania major | cathepsin L-like protease | 0.1271 | 0.2333 | 0.0911 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3171 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.3171 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1271 | 0.2333 | 0.3615 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2292 | 0.6453 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0876 | 0.0742 | 0.115 |
Echinococcus multilocularis | cysteine protease | 0.1271 | 0.2333 | 0.3615 |
Onchocerca volvulus | 0.1271 | 0.2333 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1271 | 0.2333 | 0.3615 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2292 | 0.6453 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1271 | 0.2333 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2292 | 0.6453 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0876 | 0.0742 | 0.115 |
Loa Loa (eye worm) | hypothetical protein | 0.1271 | 0.2333 | 0.2785 |
Echinococcus granulosus | cathepsin l1 | 0.0876 | 0.0742 | 0.115 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3171 | 1 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.2292 | 0.6453 | 1 |
Leishmania major | cathepsin L-like protease | 0.3171 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1271 | 0.2333 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3171 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1271 | 0.2333 | 0.3615 |
Echinococcus multilocularis | cysteine protease | 0.1271 | 0.2333 | 0.3615 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.