Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0784 | 0.033 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0115 | 0.5071 | 1 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Brugia malayi | Melatonin receptor type 1A | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0115 | 0.5071 | 0.3597 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | neuropeptide receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | opsin-like receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | Dopamine receptor protein 2 | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.006 | 0.1947 | 0.3209 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | larval opioid receptor | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | follicle stimulating hormone receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0067 | 0.2302 | 0.1752 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0038 | 0.0666 | 0.5 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0067 | 0.2302 | 0.1752 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0115 | 0.5071 | 0.3597 |
Brugia malayi | Dopamine receptor protein 1 | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | amine GPCR | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | neuropeptide receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | neuropeptide receptor | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0067 | 0.2302 | 0.1752 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0115 | 0.5071 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | Dopamine receptor | 0.0067 | 0.2302 | 0.1752 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0038 | 0.0666 | 0.0426 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0091 | 0.3719 | 0.6931 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0115 | 0.5071 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | RE15519p | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | G protein-coupled receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1929 | 0.1534 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0067 | 0.2302 | 0.1752 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | G-protein coupled receptor | 0.0067 | 0.2302 | 0.1752 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0067 | 0.2302 | 0.5 |
Brugia malayi | sulfakinin receptor protein | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | GnHR receptor homolog | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | biogenic amine receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | histamine h1 receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | amine GPCR | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0115 | 0.5071 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | STE/STE11/ASK protein kinase | 0.006 | 0.1947 | 0.1552 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | opsin-like receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | biogenic amine receptor | 0.0067 | 0.2302 | 0.1752 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | Serotonin receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Brugia malayi | Serotonin receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | amine GPCR | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | ORL1-like opioid receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0051 | 0.1387 | 0.1637 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | protein kinase | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0067 | 0.2302 | 0.1752 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0074 | 0.2739 | 0.0568 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0079 | 0.2998 | 0.5294 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0074 | 0.2739 | 0.2221 |
Schistosoma mansoni | biogenic amine receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0091 | 0.3719 | 0.3415 |
Schistosoma mansoni | amine GPCR | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | neuropeptide F receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0067 | 0.2302 | 0.1925 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0067 | 0.2302 | 0.5 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0115 | 0.5071 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | myosin xvIII | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | opsin-like receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | amine GPCR | 0.0067 | 0.2302 | 0.1752 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0074 | 0.2739 | 0.0568 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.006 | 0.1947 | 0.3209 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0067 | 0.2302 | 0.1925 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0055 | 0.1646 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0115 | 0.5071 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0091 | 0.3719 | 0.6931 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0067 | 0.2302 | 0.1925 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0079 | 0.2998 | 0.5294 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Brugia malayi | G-protein coupled receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.9983 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.2739 | 0.2385 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.02 | 1 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0067 | 0.2302 | 0.1925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | neuropeptide receptor | 0.0067 | 0.2302 | 0.1752 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0067 | 0.2302 | 0.1925 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | hypothetical protein | 0.0067 | 0.2302 | 0.1752 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0115 | 0.5071 | 0.4719 |
Brugia malayi | AKH receptor | 0.0067 | 0.2302 | 0.1752 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0111 | 0.4875 | 0.9555 |
Schistosoma mansoni | adenoreceptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0115 | 0.5071 | 0.4719 |
Schistosoma mansoni | protein kinase | 0.02 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0067 | 0.2302 | 0.1752 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.02 | 1 | 1 |
Onchocerca volvulus | 0.0067 | 0.2302 | 0.5 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0067 | 0.2302 | 0.1752 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 0.2302 | 0.1752 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.