Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.1337 | 0.0337 | 1 |
Onchocerca volvulus | 0.1016 | 0 | 0.5 | |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.5101 | 0.4289 | 1 |
Onchocerca volvulus | 0.1016 | 0 | 0.5 | |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.1337 | 0.0337 | 0.0337 |
Schistosoma mansoni | choline o-acyltransferase | 0.1016 | 0 | 0.5 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.1337 | 0.0337 | 0.0786 |
Loa Loa (eye worm) | hypothetical protein | 1.054 | 1 | 1 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.5101 | 0.4289 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.5101 | 0.4289 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.5101 | 0.4289 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.1337 | 0.0337 | 0.0786 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.5101 | 0.4289 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.1337 | 0.0337 | 0.0786 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.1337 | 0.0337 | 0.0786 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.1337 | 0.0337 | 0.0337 |
Schistosoma mansoni | choline o-acyltransferase | 0.1016 | 0 | 0.5 |
Onchocerca volvulus | 0.1016 | 0 | 0.5 | |
Onchocerca volvulus | 0.1016 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.