Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | fatty acid elongase, putative | 0.0443 | 0.5 | 0.5 |
Leishmania major | fatty acid elongase, putative | 0.0443 | 0.5 | 0.5 |
Toxoplasma gondii | GNS1/SUR4 family protein | 0.0443 | 0.5 | 0.5 |
Plasmodium falciparum | long chain fatty acid elongation enzyme, putative | 0.0443 | 0.5 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0443 | 0.5 | 0.5 |
Toxoplasma gondii | integral membrane protein, GNS1/SUR4 family protein, putative | 0.0443 | 0.5 | 0.5 |
Leishmania major | fatty acid elongase, putative | 0.0443 | 0.5 | 0.5 |
Loa Loa (eye worm) | GNS1/SUR4 family protein | 0.0443 | 0.5 | 0.5 |
Brugia malayi | GNS1/SUR4 family protein | 0.0443 | 0.5 | 0.5 |
Leishmania major | fatty acid elongase, putative | 0.0443 | 0.5 | 0.5 |
Plasmodium vivax | GNS1/SUR4 domain containing protein | 0.0443 | 0.5 | 0.5 |
Plasmodium falciparum | fatty acid elongation protein, GNS1/SUR4 family, putative | 0.0443 | 0.5 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0443 | 0.5 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0443 | 0.5 | 0.5 |
Trypanosoma brucei | Fatty acid elongase | 0.0443 | 0.5 | 0.5 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0443 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.