Detailed information for compound 925951

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 383.66 | Formula: C16H13Cl3N4O
  • H donors: 3 H acceptors: 2 LogP: 4.27 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cc(Cl)cc(c1)C(=O)Nc1ccc(cc1)c1c[nH]c(n1)N.Cl
  • InChi: 1S/C16H12Cl2N4O.ClH/c17-11-5-10(6-12(18)7-11)15(23)21-13-3-1-9(2-4-13)14-8-20-16(19)22-14;/h1-8H,(H,21,23)(H3,19,20,22);1H
  • InChiKey: SOCBTGBCXHPVIZ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0221 1 1
Schistosoma mansoni amine GPCR 0.0221 1 1
Schistosoma mansoni adenoreceptor 0.0221 1 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0221 1 1
Brugia malayi neuropeptide F receptor 0.0221 1 1
Leishmania major ubiquitin-activating enzyme e1, putative 0.0069 0.1661 1
Echinococcus multilocularis allatostatin A receptor 0.0221 1 1
Schistosoma mansoni hypothetical protein 0.0221 1 1
Plasmodium falciparum ubiquitin-activating enzyme E1 0.0131 0.5036 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0221 1 1
Echinococcus multilocularis somatostatin receptor 0.0221 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0221 1 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0221 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0221 1 1
Schistosoma mansoni neuropeptide receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0221 1 1
Brugia malayi AKH receptor 0.0221 1 1
Brugia malayi ORL1-like opioid receptor 0.0221 1 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0221 1 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0221 1 1
Echinococcus multilocularis orexin receptor type 2 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) TYRA-2 protein 0.0221 1 1
Echinococcus granulosus g-protein coupled receptor 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0221 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0221 1 1
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0101 0.3401 1
Trichomonas vaginalis ubiquitin-activating enzyme E1c, putative 0.0101 0.3401 1
Schistosoma mansoni hypothetical protein 0.0221 1 1
Brugia malayi Dopamine receptor protein 1 0.0221 1 1
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.007 0.1687 0.1536
Brugia malayi G protein-coupled receptor 0.0221 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0221 1 1
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0052 0.0732 0.1901
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Echinococcus granulosus g protein coupled receptor 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Brugia malayi Serotonin receptor 0.0221 1 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0221 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0221 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Brugia malayi G-protein coupled receptor 0.0221 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Brugia malayi putative neuropeptide receptor NPR1 0.0221 1 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0221 1 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Echinococcus granulosus neuropeptide receptor A26 0.0221 1 1
Schistosoma mansoni neuropeptide receptor 0.0221 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0221 1 1
Brugia malayi putative neuropeptide receptor 0.0221 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0221 1 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0221 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0221 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0221 1 1
Brugia malayi follicle stimulating hormone receptor 0.0221 1 1
Echinococcus multilocularis neuropeptide receptor 0.0221 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0221 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0221 1 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0221 1 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0221 1 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0221 1 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0221 1 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0221 1 1
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0052 0.0704 0.0475
Echinococcus granulosus neuropeptide receptor 0.0221 1 1
Trichomonas vaginalis ubiquitin-activating enzyme E1 X, putative 0.0045 0.0315 0.0636
Schistosoma mansoni amine GPCR 0.0221 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0221 1 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0221 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0221 1 1
Brugia malayi hypothetical protein 0.0221 1 1
Brugia malayi hypothetical protein 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Onchocerca volvulus 0.0221 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0704 0.0475
Brugia malayi hypothetical protein 0.0221 1 1
Echinococcus granulosus fmrfamide receptor 0.0221 1 1
Brugia malayi hypothetical protein 0.0221 1 1
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0044 0.024 0.0411
Onchocerca volvulus 0.0221 1 0.5
Echinococcus granulosus peptide allatostatin:somatostatin 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0221 1 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0221 1 1
Brugia malayi Dopamine receptor protein 2 0.0221 1 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0221 1 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Loa Loa (eye worm) ectopic membrane ruffles in embryo protein 1 0.007 0.1687 0.1482
Plasmodium vivax ubiquitin activating enzyme, putative 0.0052 0.0704 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0221 1 1
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0049 0.0539 0.2098
Echinococcus multilocularis serotonin receptor 0.0221 1 1
Echinococcus multilocularis g protein coupled receptor 0.0221 1 1
Echinococcus multilocularis g protein coupled receptor 0.0221 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Loa Loa (eye worm) ube1-prov protein 0.0131 0.5036 0.4913
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0221 1 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Brugia malayi Melatonin receptor type 1A 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni ubiquitin-activating enzyme E1 0.0105 0.3625 0.3509
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus multilocularis fmrfamide receptor 0.0221 1 1
Brugia malayi Ectopic membrane ruffles in embryo protein 1 0.007 0.1687 0.1482
Giardia lamblia Ubiquitin-conjugating enzyme E1 0.0069 0.1661 0.5
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Brugia malayi hypothetical protein 0.0221 1 1
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.007 0.1687 0.3017
Echinococcus granulosus orexin receptor type 2 0.0221 1 1
Echinococcus granulosus neuropeptide receptor 0.0221 1 1
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0069 0.1661 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 1 1
Schistosoma mansoni clathrin coat associated protein ap-50 0.0081 0.2278 0.2138
Onchocerca volvulus 0.0221 1 0.5
Toxoplasma gondii hypothetical protein 0.0052 0.0704 0.3205
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0221 1 1
Brugia malayi larval opioid receptor 0.0221 1 1
Brugia malayi neuropeptide F receptor 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0221 1 1
Brugia malayi hypothetical protein 0.0221 1 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0221 1 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus sex peptide receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus multilocularis neuropeptide s receptor 0.0221 1 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Brugia malayi Serotonin receptor 0.0221 1 1
Trypanosoma cruzi ubiquitin-activating enzyme E1, putative 0.0069 0.1661 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0221 1 1
Echinococcus multilocularis g protein coupled receptor 0.0221 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 1 1
Echinococcus granulosus ubiquitin modifier activating enzyme 1 0.0131 0.5036 0.4913
Schistosoma mansoni hypothetical protein 0.0221 1 1
Brugia malayi hypothetical protein 0.0221 1 1
Echinococcus multilocularis fmrfamide receptor 0.0221 1 1
Echinococcus multilocularis serotonin receptor 0.0221 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0221 1 1
Brugia malayi ThiF family protein 0.0052 0.0704 0.0475
Schistosoma mansoni biogenic amine receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0221 1 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus allatostatin A receptor 0.0221 1 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0221 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0221 1 1
Trypanosoma cruzi NEDD8-activating enzyme E1 regulatory subunit, putative 0.0044 0.024 0.1447
Onchocerca volvulus 0.0221 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0221 1 1
Schistosoma mansoni opsin-like receptor 0.0221 1 1
Toxoplasma gondii NEDD8-activating enzyme E1 catalytic subunit 0.007 0.1687 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus multilocularis neuropeptide receptor 0.0221 1 1
Trypanosoma cruzi ubiquitin-activating enzyme E1, putative 0.0069 0.1661 1
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0052 0.0704 0.0535
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus multilocularis sex peptide receptor 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Schistosoma mansoni neuropeptide F-like receptor 0.0221 1 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0221 1 1
Schistosoma mansoni neuropeptide receptor 0.0221 1 1
Schistosoma mansoni clathrin coat associated protein ap-50 0.0081 0.2278 0.2138
Brugia malayi Dopamine receptor 0.0221 1 1
Echinococcus granulosus neuropeptide s receptor 0.0221 1 1
Echinococcus granulosus somatostatin receptor 0.0221 1 1
Echinococcus granulosus dro:myosuppressin receptor 0.0221 1 1
Echinococcus multilocularis ubiquitin modifier activating enzyme 1 0.0131 0.5036 0.4913
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni neuropeptide receptor 0.0221 1 1
Echinococcus granulosus g protein coupled receptor 0.0221 1 1
Echinococcus multilocularis ubiquitin modifier activating enzyme 6 0.0131 0.5036 0.4913
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni amine GPCR 0.0221 1 1
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0101 0.3401 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0221 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Schistosoma mansoni opsin-like receptor 0.0221 1 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0221 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0221 1 1
Schistosoma mansoni histamine h1 receptor 0.0221 1 1
Brugia malayi GnHR receptor homolog 0.0221 1 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0221 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0221 1 1
Leishmania major ubiquitin-activating enzyme e1, putative 0.0049 0.0539 0.2098
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0044 0.024 0.0411
Echinococcus multilocularis neuropeptides capa receptor 0.0221 1 1
Echinococcus granulosus hypothetical protein 0.0221 1 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0221 1 1
Echinococcus multilocularis g-protein coupled receptor 0.0221 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0221 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0221 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.0221 1 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Echinococcus granulosus NEDD8 activating enzyme E1 catalytic subunit 0.007 0.1687 0.1482
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0221 1 1
Echinococcus multilocularis NEDD8 activating enzyme E1 catalytic subunit 0.007 0.1687 0.1482
Brugia malayi sulfakinin receptor protein 0.0221 1 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0221 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0221 1 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0221 1 1
Brugia malayi ube1-prov protein 0.0131 0.5036 0.4913
Schistosoma mansoni amine GPCR 0.0221 1 1
Schistosoma mansoni opsin-like receptor 0.0221 1 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0221 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Echinococcus granulosus ubiquitin modifier activating enzyme 6 0.0131 0.5036 0.4913
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0221 1 1
Echinococcus granulosus serotonin receptor 0.0221 1 1
Schistosoma mansoni app binding protein 0.0044 0.024 0.0063
Brugia malayi hypothetical protein 0.0221 1 1
Brugia malayi G-protein coupled receptor 0.0221 1 1
Schistosoma mansoni biogenic amine receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0221 1 1
Echinococcus granulosus g protein coupled receptor 0.0221 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0221 1 1
Brugia malayi hypothetical protein 0.0221 1 1
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0131 0.5036 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0221 1 1
Entamoeba histolytica ubiquitin-activating enzyme E1 1, putative 0.0101 0.3401 0.6591
Brugia malayi RE15519p 0.0221 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Schistosoma mansoni hypothetical protein 0.0221 1 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0221 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0221 1 1
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0052 0.0704 0.0475
Schistosoma mansoni amine GPCR 0.0221 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0221 1 1
Schistosoma mansoni myosin xvIII 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0221 1 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0221 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0221 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Loa Loa (eye worm) hypothetical protein 0.0221 1 1
Onchocerca volvulus 0.0221 1 0.5
Schistosoma mansoni biogenic amine receptor 0.0221 1 1

Activities

Activity type Activity value Assay description Source Reference
TCID50 (ADMET) = 387 uM Cytotoxicity against human HaCaT cells after 12 to 18 hrs by MTT assay ChEMBL. 25137478

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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