Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0149 | 0.5 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin l1 | 0.0029 | 0.086 | 0.086 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0051 | 0.2513 | 0.24 |
Toxoplasma gondii | cathepsin CPL | 0.0029 | 0.086 | 0.2802 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | larval opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | ctsf protein | 0.0029 | 0.086 | 0.0722 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Onchocerca volvulus | Cathepsin F homolog | 0.0029 | 0.086 | 0.2619 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0053 | 0.2688 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 1 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0051 | 0.2513 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0021 | 0.0274 | 0.0274 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0053 | 0.2688 | 0.2688 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0153 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G protein-coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0029 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0149 | 0.0149 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | fibroinase | 0.0029 | 0.086 | 0.0722 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0029 | 0.086 | 0.086 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | RNA helicase, putative | 0.0138 | 0.8886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0053 | 0.2688 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0149 | 0.1732 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | GnHR receptor homolog | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | sulfakinin receptor protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Brugia malayi | RE15519p | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0053 | 0.2688 | 0.3024 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor protein 1 | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0029 | 0.086 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0029 | 0.086 | 0.086 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | ORL1-like opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0029 | 0.086 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | AKH receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0149 | 0.0149 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Toxoplasma gondii | cathepsin B | 0.0053 | 0.2688 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0051 | 0.2513 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cysteine peptidase A (CPA) | 0.0029 | 0.086 | 0.2802 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Melatonin receptor type 1A | 0.0051 | 0.2513 | 0.2513 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0149 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Brugia malayi | putative neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.086 | 0.0722 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | histamine h1 receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0021 | 0.0274 | 0.0274 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.0722 |
Schistosoma mansoni | myosin xvIII | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Dopamine receptor protein 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | cathepsin B | 0.0053 | 0.2688 | 0.2577 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0168 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0029 | 0.086 | 0.0722 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0149 | 0.5 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0021 | 0.0274 | 0.3182 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0053 | 0.2688 | 0.2688 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Entamoeba histolytica | cysteine protease, putative | 0.0029 | 0.086 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0149 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.8886 | 0.8886 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | cysteine protease | 0.0029 | 0.086 | 0.0722 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | cathepsin l1 | 0.0021 | 0.0274 | 0.0274 |
Brugia malayi | cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 12 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 14 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit colony formation of Ishikawa human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 19 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 20 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 21 % | The concentration to inhibit colony formation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 32 % | The concentration to inhibit cell proliferation of LNCaP human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 40 % | The concentration to inhibit cell proliferation of LNCaP human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 44 % | The concentration to inhibit colony formation of MDA-MB-231 humantumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 45 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.