Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cyclins | 0.0784 | 0.1903 | 0.5972 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.062 | 0.1406 | 0.4196 |
Giardia lamblia | Cyclin A | 0.0784 | 0.1903 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0727 | 0.1731 | 0.5359 |
Entamoeba histolytica | cyclin, domain containing protein | 0.0233 | 0.0231 | 0.1078 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0784 | 0.1903 | 0.1711 |
Loa Loa (eye worm) | CMGC/CDK/CDK9 protein kinase | 0.062 | 0.1406 | 0.1202 |
Entamoeba histolytica | cyclin family protein | 0.0784 | 0.1903 | 0.8873 |
Trichomonas vaginalis | cyclins, putative | 0.0784 | 0.1903 | 0.8737 |
Loa Loa (eye worm) | cyclin C | 0.1155 | 0.303 | 0.2865 |
Schistosoma mansoni | cyclin B3 | 0.0784 | 0.1903 | 0.5972 |
Echinococcus granulosus | cyclin b3 | 0.0784 | 0.1903 | 0.5972 |
Trichomonas vaginalis | cyclin D, putative | 0.0784 | 0.1903 | 0.8737 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.1155 | 0.303 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0784 | 0.1903 | 0.8737 |
Echinococcus granulosus | cyclins | 0.0784 | 0.1903 | 0.5972 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0784 | 0.1903 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0784 | 0.1903 | 1 |
Toxoplasma gondii | hypothetical protein | 0.055 | 0.1194 | 1 |
Echinococcus multilocularis | cyclins | 0.0784 | 0.1903 | 0.5972 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0784 | 0.1903 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.2019 | 0.5653 | 0.555 |
Trypanosoma cruzi | cyclin 6, putative | 0.0784 | 0.1903 | 1 |
Echinococcus granulosus | cyclin | 0.1155 | 0.303 | 1 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.1155 | 0.303 | 1 |
Entamoeba histolytica | cyclin, putative | 0.0784 | 0.1903 | 0.8873 |
Trichomonas vaginalis | cyclin D, putative | 0.0784 | 0.1903 | 0.8737 |
Echinococcus multilocularis | cyclin B | 0.0784 | 0.1903 | 0.5972 |
Trichomonas vaginalis | cyclins, putative | 0.0784 | 0.1903 | 0.8737 |
Brugia malayi | Cyclin C | 0.1155 | 0.303 | 0.2865 |
Echinococcus granulosus | cyclins | 0.0784 | 0.1903 | 0.5972 |
Entamoeba histolytica | cyclin family protein | 0.0784 | 0.1903 | 0.8873 |
Echinococcus multilocularis | cyclins | 0.0784 | 0.1903 | 0.5972 |
Echinococcus multilocularis | cyclin b3 | 0.0784 | 0.1903 | 0.5972 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.1155 | 0.303 | 1 |
Onchocerca volvulus | 0.0784 | 0.1903 | 1 | |
Entamoeba histolytica | cyclin, domain containing protein | 0.0233 | 0.0231 | 0.1078 |
Echinococcus multilocularis | cyclins | 0.0784 | 0.1903 | 0.5972 |
Trichomonas vaginalis | cyclins, putative | 0.0784 | 0.1903 | 0.8737 |
Entamoeba histolytica | hypothetical protein | 0.0233 | 0.0231 | 0.1078 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.2019 | 0.5653 | 0.555 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.062 | 0.1406 | 0.4196 |
Trichomonas vaginalis | cyclins, putative | 0.0784 | 0.1903 | 0.8737 |
Plasmodium falciparum | cyclin | 0.0784 | 0.1903 | 1 |
Echinococcus granulosus | cyclins | 0.0784 | 0.1903 | 0.5972 |
Plasmodium vivax | cyclin 4, putative | 0.0233 | 0.0231 | 0.5 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0784 | 0.1903 | 0.5972 |
Echinococcus multilocularis | cyclins | 0.0784 | 0.1903 | 0.5972 |
Plasmodium vivax | hypothetical protein, conserved | 0.0233 | 0.0231 | 0.5 |
Brugia malayi | cyclin-dependent kinase 9 | 0.062 | 0.1406 | 0.1202 |
Schistosoma mansoni | cyclin B | 0.0784 | 0.1903 | 0.5972 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0727 | 0.1731 | 0.5359 |
Trichomonas vaginalis | cyclin B, putative | 0.0784 | 0.1903 | 0.8737 |
Trichomonas vaginalis | cyclin B, putative | 0.0784 | 0.1903 | 0.8737 |
Trichomonas vaginalis | cyclin A, putative | 0.0784 | 0.1903 | 0.8737 |
Echinococcus multilocularis | cyclins | 0.0784 | 0.1903 | 0.5972 |
Trypanosoma cruzi | cyclin, putative | 0.0784 | 0.1903 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.062 | 0.1406 | 0.4196 |
Echinococcus granulosus | cyclin B3 1 | 0.0784 | 0.1903 | 0.5972 |
Echinococcus multilocularis | cyclin B3 1 | 0.0784 | 0.1903 | 0.5972 |
Schistosoma mansoni | kinase | 0.062 | 0.1406 | 0.4196 |
Trichomonas vaginalis | cyclin H, putative | 0.0863 | 0.2144 | 1 |
Plasmodium vivax | cyclin homologue, putative | 0.0233 | 0.0231 | 0.5 |
Plasmodium vivax | cyclin dependent kinase binding protein, putative | 0.0233 | 0.0231 | 0.5 |
Echinococcus multilocularis | cyclin | 0.1155 | 0.303 | 1 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0784 | 0.1903 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0784 | 0.1903 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0784 | 0.1903 | 0.1711 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0784 | 0.1903 | 0.1711 |
Echinococcus granulosus | cyclins | 0.0784 | 0.1903 | 0.5972 |
Trichomonas vaginalis | cyclins, putative | 0.0784 | 0.1903 | 0.8737 |
Entamoeba histolytica | hypothetical protein | 0.0863 | 0.2144 | 1 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0784 | 0.1903 | 0.5972 |
Entamoeba histolytica | cyclin, putative | 0.0784 | 0.1903 | 0.8873 |
Trichomonas vaginalis | cyclin B, putative | 0.0784 | 0.1903 | 0.8737 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0784 | 0.1903 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0784 | 0.1903 | 0.8737 |
Leishmania major | cyclin | 0.0784 | 0.1903 | 1 |
Entamoeba histolytica | cyclin C, putative | 0.0233 | 0.0231 | 0.1078 |
Echinococcus granulosus | cyclin B | 0.0784 | 0.1903 | 0.5972 |
Schistosoma mansoni | cyclins | 0.0784 | 0.1903 | 0.5972 |
Echinococcus multilocularis | cyclins | 0.0784 | 0.1903 | 0.5972 |
Giardia lamblia | Hypothetical protein | 0.0784 | 0.1903 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0784 | 0.1903 | 0.8737 |
Entamoeba histolytica | protein kinase domain containing protein | 0.062 | 0.1406 | 0.6555 |
Loa Loa (eye worm) | hypothetical protein | 0.0784 | 0.1903 | 0.1711 |
Trichomonas vaginalis | cyclin B3, putative | 0.0784 | 0.1903 | 0.8737 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0784 | 0.1903 | 0.1711 |
Echinococcus multilocularis | cyclins | 0.0784 | 0.1903 | 0.5972 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.345 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.