Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | maltase-glucoamylase (alpha-glucosidase) | Starlite/ChEMBL | References |
Homo sapiens | sucrase-isomaltase (alpha-glucosidase) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0623 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0203 | 0 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0623 | 1 | 1 |
Mycobacterium ulcerans | adenosine deaminase | 0.0623 | 1 | 0.5 |
Onchocerca volvulus | 0.0284 | 0.1941 | 0.1941 | |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.5169 | 0.5169 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0623 | 1 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0423 | 0.5247 | 0.5247 |
Schistosoma mansoni | adenosine deaminase-related | 0.0623 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0623 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0623 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0423 | 0.5247 | 0.5247 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0623 | 1 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0623 | 1 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0623 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0423 | 0.5247 | 0.5247 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0423 | 0.5247 | 0.5247 |
Echinococcus multilocularis | adenosine deaminase | 0.0623 | 1 | 1 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0623 | 1 | 1 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0623 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.5169 | 0.5169 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0623 | 1 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0623 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.5169 | 0.5169 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0623 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0623 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0423 | 0.5247 | 0.5247 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.5169 | 0.5169 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0203 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0203 | 0 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0623 | 1 | 1 |
Plasmodium falciparum | adenosine deaminase | 0.0623 | 1 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0203 | 0 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0203 | 0 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0423 | 0.5247 | 0.5247 |
Schistosoma mansoni | alpha-glucosidase | 0.0423 | 0.5247 | 0.5247 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.