Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.0856 | 0.0864 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.0856 | 0.0864 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trypanosoma brucei | trans-sialidase | 0.0301 | 0.2472 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trichomonas vaginalis | Sialidase-1 precursor, putative | 0.1132 | 1 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Entamoeba histolytica | Pten 3-phosphoinositide phosphatase, putative | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.1121 | 0.9904 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0301 | 0.2472 | 0.9998 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Leishmania major | protein-tyrosine phosphatase 1-like protein | 0.0028 | 0 | 0.5 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, putative | 0.0301 | 0.2472 | 0.9998 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0704 | 0.6121 | 0.6121 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Leishmania major | tyrosine specific protein phosphatase, putative | 0.0028 | 0 | 0.5 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.0856 | 0.0864 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0028 | 0 | 0.5 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trypanosoma brucei | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0301 | 0.2472 | 0.9998 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.1121 | 0.9904 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.1121 | 0.9904 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Trypanosoma brucei | trans-sialidase, putative | 0.0301 | 0.2472 | 1 |
Onchocerca volvulus | 0.0028 | 0 | 0.5 | |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.1121 | 0.9904 | 1 |
Giardia lamblia | Protein tyrosine phosphatase | 0.0028 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.1121 | 0.9904 | 1 |
Onchocerca volvulus | 4.1 G protein, putative homolog | 0.0028 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0301 | 0.2472 | 0.9998 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0301 | 0.2472 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.