Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | WEE1 G2 checkpoint kinase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 0 | 0.5 |
Leishmania major | protein kinase, putative,serine/threonine protein kinase, putative | 0.0069 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | phospho-N-acetylmuramoyl-pentapeptide-transferase | 0.1527 | 1 | 0.5 |
Chlamydia trachomatis | phospho-N-acetylmuramoyl-pentapeptide-transferase | 0.058 | 0.3509 | 0.5 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0069 | 0 | 0.5 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 0 | 0.5 |
Treponema pallidum | phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) | 0.058 | 0.3509 | 0.5 |
Mycobacterium ulcerans | phospho-N-acetylmuramoyl-pentapeptide-transferase | 0.1527 | 1 | 0.5 |
Trypanosoma brucei | wee1-like protein kinase | 0.0069 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX | 0.1527 | 1 | 0.5 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.