Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0093 | 0.0471 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0471 | 0.0368 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0093 | 0.0471 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0093 | 0.0471 | 0.5 |
Mycobacterium leprae | Probable Ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit) | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | acetylcholinesterase | 0.0093 | 0.0471 | 0.0368 |
Onchocerca volvulus | 0.0093 | 0.0471 | 0.0148 | |
Brugia malayi | Cytochrome c type-1 | 0.0105 | 0.0569 | 0.0352 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0471 | 0.0209 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.055 | 0.4216 | 1 |
Wolbachia endosymbiont of Brugia malayi | cytochrome c2 | 0.0105 | 0.0569 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.055 | 0.4216 | 1 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0289 | 0.2078 | 0.255 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0343 | 0.252 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0093 | 0.0471 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.055 | 0.4216 | 1 |
Plasmodium vivax | cytochrome c, putative | 0.0105 | 0.0569 | 0.2258 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0093 | 0.0471 | 1 |
Schistosoma mansoni | gliotactin | 0.0093 | 0.0471 | 0.0368 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0093 | 0.0471 | 0.0368 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0343 | 0.252 | 1 |
Onchocerca volvulus | 0.0093 | 0.0471 | 0.0148 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0093 | 0.0471 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0471 | 0.0368 |
Echinococcus multilocularis | acetylcholinesterase | 0.055 | 0.4216 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0093 | 0.0471 | 0.0368 |
Onchocerca volvulus | 0.0093 | 0.0471 | 0.0148 | |
Schistosoma mansoni | cytochrome c | 0.0105 | 0.0569 | 0.0621 |
Echinococcus multilocularis | carboxylesterase 5A | 0.055 | 0.4216 | 1 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0343 | 0.252 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0471 | 0.0368 |
Echinococcus granulosus | cytochrome c | 0.0105 | 0.0569 | 0.0262 |
Plasmodium falciparum | cytochrome c, putative | 0.0105 | 0.0569 | 0.2258 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0093 | 0.0471 | 0.0368 |
Toxoplasma gondii | cytochrome c, putative | 0.0105 | 0.0569 | 0.2258 |
Onchocerca volvulus | 0.0093 | 0.0471 | 0.0148 | |
Echinococcus granulosus | acetylcholinesterase | 0.055 | 0.4216 | 1 |
Echinococcus multilocularis | cytochrome c | 0.0105 | 0.0569 | 0.0262 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0093 | 0.0471 | 0.0368 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0093 | 0.0471 | 0.5 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0343 | 0.252 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0471 | 0.0209 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0093 | 0.0471 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0471 | 0.0368 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0093 | 0.0471 | 0.5 |
Giardia lamblia | Telomerase catalytic subunit | 0.0343 | 0.252 | 0.5 |
Onchocerca volvulus | 0.0093 | 0.0471 | 0.0148 | |
Loa Loa (eye worm) | carboxylesterase | 0.0093 | 0.0471 | 0.0368 |
Loa Loa (eye worm) | cytochrome c type-1 | 0.0105 | 0.0569 | 0.0621 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0471 | 0.0368 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0471 | 0.0209 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0343 | 0.252 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.055 | 0.4216 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.055 | 0.4216 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.055 | 0.4216 | 0.5667 |
Loa Loa (eye worm) | carboxylesterase | 0.055 | 0.4216 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.055 | 0.4216 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0471 | 0.0209 |
Brugia malayi | Telomerase reverse transcriptase | 0.0914 | 0.7189 | 1 |
Loa Loa (eye worm) | STAT protein | 0.0289 | 0.2078 | 0.45 |
Loa Loa (eye worm) | hypothetical protein | 0.055 | 0.4216 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.055 | 0.4216 | 0.5667 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0343 | 0.252 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0471 | 0.0368 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0343 | 0.252 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0471 | 0.0368 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.