Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0073 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0073 | 0.0073 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0073 | 0.5 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0073 | 0.5 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.0086 | 0.26 | 0.5951 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0073 | 0.0166 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0073 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0073 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0073 | 0.5 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0073 | 0.5 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0062 | 0.136 | 0.3111 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0073 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0073 | 0.0166 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0073 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0073 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0073 | 0.0073 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0183 | 0.7499 | 1 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.0086 | 0.26 | 0.26 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.0121 | 0.437 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0073 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0073 | 0.0166 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0073 | 0.0073 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0062 | 0.136 | 0.136 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0073 | 0.0073 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0073 | 0.0073 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0073 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0073 | 0.5 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0073 | 0.5 |
Onchocerca volvulus | 0.0036 | 0.0073 | 0.5 | |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0073 | 0.0073 |
Onchocerca volvulus | 0.0036 | 0.0073 | 0.5 | |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0073 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0073 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0073 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0073 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0073 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0073 | 0.5 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0062 | 0.136 | 0.3111 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0073 | 0.5 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0073 | 0.0073 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0086 | 0.26 | 0.5951 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0073 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0073 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0073 | 0.5 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0073 | 0.5 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0073 | 0.0073 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.0183 | 0.7499 | 1 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.0183 | 0.7499 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0073 | 0.0166 |
Onchocerca volvulus | 0.0036 | 0.0073 | 0.5 | |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0054 | 0.0978 | 0.2238 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.