Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0156 | 0.6874 | 1 |
Brugia malayi | Lipase family protein | 0.0156 | 0.6874 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0111 | 0.4236 | 0.6162 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.0156 | 0.6874 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0156 | 0.6874 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0044 | 0.0272 | 0.0272 |
Brugia malayi | amidase | 0.0111 | 0.4236 | 0.6162 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0044 | 0.0272 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0156 | 0.6874 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0044 | 0.0272 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0044 | 0.0272 | 0.0396 |
Trypanosoma brucei | lipase domain protein, putative | 0.0156 | 0.6874 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0044 | 0.0272 | 0.5 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0136 | 0.5672 | 0.8251 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.4236 | 0.6162 |
Loa Loa (eye worm) | lipase | 0.0156 | 0.6874 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0111 | 0.4236 | 0.6162 |
Trypanosoma brucei | lipase domain protein, putative | 0.0156 | 0.6874 | 0.5 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0156 | 0.6874 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0111 | 0.4236 | 0.6162 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0044 | 0.0272 | 0.0396 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0044 | 0.0272 | 0.0272 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.0156 | 0.6874 | 1 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0156 | 0.6874 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0044 | 0.0272 | 0.5 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0111 | 0.4236 | 0.4236 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0136 | 0.5672 | 0.8251 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0111 | 0.4236 | 0.6162 |
Onchocerca volvulus | 0.0156 | 0.6874 | 0.5 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0044 | 0.0272 | 0.5 |
Schistosoma mansoni | amidase | 0.0111 | 0.4236 | 0.4236 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.