Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0496 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0258 | 0.0984 | 0.0984 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0258 | 0.0984 | 0.0984 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0496 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0258 | 0.0984 | 0.0984 |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0496 | 1 | 1 |
Onchocerca volvulus | 0.0496 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Onchocerca volvulus | 0.0496 | 1 | 1 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0258 | 0.0984 | 0.0984 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.3853 | 0.3853 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0258 | 0.0984 | 0.0984 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0496 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.3853 | 0.3853 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.3853 | 0.3853 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.3853 | 0.3853 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0496 | 1 | 1 |
Onchocerca volvulus | 0.0496 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.3853 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0496 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0496 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0496 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0258 | 0.0984 | 0.0984 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0258 | 0.0984 | 0.0984 |
Echinococcus granulosus | cysteine protease | 0.0258 | 0.0984 | 0.0984 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0496 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0496 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0496 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0334 | 0.3853 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0496 | 1 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0496 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.0258 | 0.0984 | 0.0984 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0334 | 0.3853 | 0.3853 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0496 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0496 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.3853 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.0984 | 0.0984 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0496 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0496 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0258 | 0.0984 | 0.0984 |
Onchocerca volvulus | 0.0496 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0334 | 0.3853 | 0.3853 |
Onchocerca volvulus | 0.0496 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0258 | 0.0984 | 0.0984 |
Brugia malayi | Cathepsin L-like precursor | 0.0496 | 1 | 1 |
Onchocerca volvulus | 0.0496 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0334 | 0.3853 | 0.3853 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0496 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0496 | 1 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0258 | 0.0984 | 0.0984 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0496 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0496 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0258 | 0.0984 | 0.0984 |
Echinococcus granulosus | cathepsin l1 | 0.0334 | 0.3853 | 0.3853 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.3853 | 0.3853 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0496 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0334 | 0.3853 | 0.3853 |
Toxoplasma gondii | cathepsin CPL | 0.0496 | 1 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0496 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0496 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0496 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0496 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0496 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0496 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0496 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0496 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0496 | 1 | 1 |
Onchocerca volvulus | 0.0496 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.