Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.0324 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0096 | 0.111 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0304 | 0.4782 | 0.4782 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0184 | 0.2659 | 1 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0127 | 0.1657 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0324 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0096 | 0.111 | 1 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0184 | 0.2659 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.0324 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0057 | 0.0411 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.06 | 1 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0096 | 0.111 | 0.111 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.111 | 0.3315 |
Echinococcus multilocularis | GPCR, family 2 | 0.0096 | 0.111 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 0.4782 | 0.4713 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0057 | 0.0411 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0096 | 0.111 | 1 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0324 | 0.0324 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0324 | 0.5 |
Onchocerca volvulus | 0.0184 | 0.2659 | 0.5 | |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0184 | 0.2659 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.06 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.3082 | 0.299 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0304 | 0.4782 | 0.4782 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0304 | 0.4782 | 0.4713 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0184 | 0.2659 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0208 | 0.3082 | 1 |
Brugia malayi | Smad1 | 0.0041 | 0.0131 | 0.0131 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0184 | 0.2659 | 1 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0184 | 0.2659 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0057 | 0.0411 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.111 | 0.0991 |
Brugia malayi | MH2 domain containing protein | 0.0041 | 0.0131 | 0.0131 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0096 | 0.111 | 0.111 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0184 | 0.2659 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0208 | 0.3082 | 0.3082 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0096 | 0.111 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.111 | 0.3315 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0184 | 0.2659 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0041 | 0.0131 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.111 | 0.3315 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0184 | 0.2659 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.111 | 0.3315 |
Brugia malayi | MH1 domain containing protein | 0.0041 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0184 | 0.2659 | 0.2561 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0057 | 0.0411 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0096 | 0.111 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0041 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0324 | 0.0195 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0096 | 0.111 | 0.0991 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0184 | 0.2659 | 1 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0184 | 0.2659 | 0.2659 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.