Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | bifunctional aminoacyl-tRNA synthetase | 0.0109 | 0.6932 | 0.6932 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.8971 | 0.6646 |
Loa Loa (eye worm) | glycyl-tRNA synthetase | 0.0109 | 0.6932 | 0.6932 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.8971 | 0.6646 |
Brugia malayi | glycyl-tRNA synthetase | 0.0109 | 0.6932 | 0.6932 |
Echinococcus granulosus | methionyl tRNA synthetase cytoplasmic | 0.014 | 1 | 1 |
Entamoeba histolytica | methionyl-tRNA synthetase, putative | 0.014 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 1 | 1 |
Echinococcus granulosus | geminin | 0.013 | 0.8971 | 0.6646 |
Loa Loa (eye worm) | multisynthetase complex auxiliary component p43 | 0.0118 | 0.7812 | 0.7812 |
Echinococcus multilocularis | methionyl tRNA synthetase, cytoplasmic | 0.014 | 1 | 1 |
Chlamydia trachomatis | methionine--tRNA ligase | 0.014 | 1 | 0.5 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.014 | 1 | 1 |
Treponema pallidum | methionyl-tRNA synthetase | 0.014 | 1 | 0.5 |
Echinococcus multilocularis | geminin | 0.013 | 0.8971 | 0.6646 |
Brugia malayi | bifunctional aminoacyl-tRNA synthetase | 0.0109 | 0.6932 | 0.6932 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.