Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0239 | 0.8929 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.016 | 0.5062 | 0.3182 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0123 | 0.3258 | 0.3649 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0239 | 0.8929 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0239 | 0.8929 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0239 | 0.8929 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0239 | 0.8929 | 1 |
Plasmodium vivax | vivapain-2 | 0.0239 | 0.8929 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0123 | 0.3258 | 0.3649 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.016 | 0.5062 | 0.567 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0123 | 0.3258 | 0.2757 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.016 | 0.5062 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.016 | 0.5062 | 0.567 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Brugia malayi | cathepsin L-like precursor | 0.016 | 0.5062 | 0.567 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0123 | 0.3258 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.016 | 0.5062 | 0.5061 |
Onchocerca volvulus | Cathepsin F homolog | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0123 | 0.3258 | 0.2757 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0123 | 0.3258 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.016 | 0.5062 | 0.567 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.11 | 0.1232 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0079 | 0.11 | 0.1232 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.5062 | 0.567 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.5062 | 0.567 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Plasmodium vivax | unspecified product | 0.0123 | 0.3258 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0079 | 0.11 | 0.1232 |
Entamoeba histolytica | cysteine proteinase, putative | 0.016 | 0.5062 | 0.3182 |
Loa Loa (eye worm) | ctsf protein | 0.0239 | 0.8929 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0123 | 0.3258 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.8929 | 1 |
Plasmodium vivax | vivapain-2 | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.5062 | 0.567 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0079 | 0.11 | 0.1232 |
Plasmodium vivax | vivapain-3 | 0.0123 | 0.3258 | 0.2757 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0123 | 0.3258 | 0.2757 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0123 | 0.3258 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.11 | 0.1232 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.11 | 0.1232 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.016 | 0.5062 | 0.5061 |
Echinococcus multilocularis | cysteine protease | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0239 | 0.8929 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0079 | 0.11 | 0.1232 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Plasmodium vivax | vivapain-1 | 0.0123 | 0.3258 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.016 | 0.5062 | 0.3182 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0123 | 0.3258 | 0.2757 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.