Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0239 | 0.8929 | 1 |
Plasmodium vivax | vivapain-2 | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0123 | 0.3258 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.016 | 0.5062 | 0.567 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.016 | 0.5062 | 0.5061 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Onchocerca volvulus | Cathepsin F homolog | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.016 | 0.5062 | 0.567 |
Leishmania major | cysteine peptidase A (CPA) | 0.0239 | 0.8929 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0079 | 0.11 | 0.1232 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.11 | 0.1232 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0079 | 0.11 | 0.1232 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0239 | 0.8929 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.5062 | 0.567 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0123 | 0.3258 | 0.2757 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0123 | 0.3258 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0123 | 0.3258 | 0.2757 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0239 | 0.8929 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.016 | 0.5062 | 0.567 |
Loa Loa (eye worm) | fibroinase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0239 | 0.8929 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0123 | 0.3258 | 0.3649 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0123 | 0.3258 | 0.2757 |
Echinococcus granulosus | cathepsin l1 | 0.016 | 0.5062 | 0.3182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.11 | 0.1232 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Brugia malayi | cathepsin L-like precursor | 0.016 | 0.5062 | 0.567 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.016 | 0.5062 | 0.3182 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0239 | 0.8929 | 1 |
Plasmodium vivax | vivapain-3 | 0.0123 | 0.3258 | 0.2757 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0079 | 0.11 | 0.1232 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.5062 | 0.567 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0239 | 0.8929 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0123 | 0.3258 | 0.2757 |
Plasmodium vivax | vivapain-1 | 0.0123 | 0.3258 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0239 | 0.8929 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0123 | 0.3258 | 0.2757 |
Plasmodium vivax | unspecified product | 0.0123 | 0.3258 | 0.2757 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0123 | 0.3258 | 0.3649 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0123 | 0.3258 | 0.2757 |
Entamoeba histolytica | cysteine proteinase, putative | 0.016 | 0.5062 | 0.3182 |
Onchocerca volvulus | 0.0239 | 0.8929 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.5062 | 0.567 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0239 | 0.8929 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0239 | 0.8929 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.016 | 0.5062 | 0.5061 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0239 | 0.8929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.11 | 0.1232 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.016 | 0.5062 | 0.3182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0239 | 0.8929 | 1 |
Leishmania major | cathepsin L-like protease | 0.0239 | 0.8929 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0239 | 0.8929 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0079 | 0.11 | 0.1232 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0239 | 0.8929 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.