Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.0078 | 0.1974 | 0.0454 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.1974 | 0.0454 |
Loa Loa (eye worm) | fibroinase | 0.0078 | 0.1974 | 0.1579 |
Loa Loa (eye worm) | cathepsin B | 0.0077 | 0.1892 | 0.1493 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.1974 | 0.0454 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.1974 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.1974 | 0.1579 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0105 | 0.3713 | 0.3713 |
Loa Loa (eye worm) | ctsf protein | 0.0078 | 0.1974 | 0.1579 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0078 | 0.1974 | 0.002 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.1974 | 0.1579 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0078 | 0.1974 | 0.002 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0173 | 0.8016 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0078 | 0.1974 | 0.1579 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0173 | 0.8016 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0078 | 0.1974 | 0.1579 |
Onchocerca volvulus | 0.0078 | 0.1974 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1974 | 0.1579 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.1974 | 0.1579 |
Onchocerca volvulus | 0.0078 | 0.1974 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.1974 | 0.1579 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0105 | 0.3713 | 0.3713 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.1974 | 0.1579 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0078 | 0.1974 | 0.1579 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Onchocerca volvulus | 0.0078 | 0.1974 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0105 | 0.3713 | 1 |
Onchocerca volvulus | 0.0078 | 0.1974 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0115 | 0.4315 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0078 | 0.1963 | 0.0116 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.1974 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0078 | 0.1974 | 0.1579 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0173 | 0.8016 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Leishmania major | cathepsin L-like protease | 0.0105 | 0.3713 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.1974 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Toxoplasma gondii | cathepsin CPC1 | 0.0173 | 0.8016 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.1974 | 0.1579 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.1974 | 0.1579 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.1974 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0077 | 0.1892 | 0.37 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.1974 | 0.1579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0077 | 0.1892 | 0.1493 |
Toxoplasma gondii | cathepsin CPC2 | 0.0078 | 0.1963 | 0.0116 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0078 | 0.1974 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Toxoplasma gondii | cathepsin CPL | 0.0078 | 0.1974 | 0.0135 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.1974 | 0.002 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Leishmania major | cathepsin L-like protease | 0.0105 | 0.3713 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0078 | 0.1974 | 0.0454 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.1974 | 0.0454 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0077 | 0.1892 | 0.1892 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.1974 | 0.002 |
Onchocerca volvulus | 0.0078 | 0.1974 | 1 | |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0078 | 0.1963 | 0.0116 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0173 | 0.8016 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.1974 | 0.0454 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0078 | 0.1974 | 0.1579 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0078 | 0.1974 | 0.002 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Onchocerca volvulus | 0.0078 | 0.1974 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Giardia lamblia | Encystation-specific protease | 0.0078 | 0.1963 | 0.0116 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0173 | 0.8016 | 0.7918 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.1974 | 0.1974 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0082 | 0.2208 | 0.2208 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0105 | 0.3713 | 0.3713 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0173 | 0.8016 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0173 | 0.8016 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0078 | 0.1974 | 0.1579 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0105 | 0.3713 | 0.3713 |
Onchocerca volvulus | Cathepsin F homolog | 0.0078 | 0.1974 | 1 |
Onchocerca volvulus | 0.0078 | 0.1974 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0078 | 0.1974 | 0.1579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.1974 | 0.3914 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0105 | 0.3713 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.