Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
504 records found | Showing page 3 of 21 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0334 | OG5_131815 | Alpha-D-glucose-1-phosphate thymidylyltransferase RmlA (dTDP-glucose synthase) ( ... |
| M. tuberculosis | Rv0350 | OG5_126744 | Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa prote ... |
| M. tuberculosis | Rv0355c | OG5_132376 | PPE family protein PPE8 |
| M. tuberculosis | Rv0363c | OG5_131639 | Probable fructose-bisphosphate aldolase Fba |
| M. tuberculosis | Rv0371c | OG5_141298 | Conserved hypothetical protein |
| M. tuberculosis | Rv0376c | OG5_138104 | Conserved hypothetical protein |
| M. tuberculosis | Rv0379 | OG5_233487 | Possible protein transport protein SecE2 |
| M. tuberculosis | Rv0388c | OG5_135481 | PPE family protein PPE9 |
| M. tuberculosis | Rv0391 | OG5_126775 | Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) |
| M. tuberculosis | Rv0403c | No group | Probable conserved membrane protein MmpS1 |
| M. tuberculosis | Rv0404 | OG5_126609 | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthas ... |
| M. tuberculosis | Rv0410c | OG5_210922 | Serine/threonine-protein kinase PknG (protein kinase G) (STPK G) |
| M. tuberculosis | Rv0411c | OG5_127777 | Probable glutamine-binding lipoprotein GlnH (GLNBP) |
| M. tuberculosis | Rv0429c | OG5_128237 | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) |
| M. tuberculosis | Rv0432 | OG5_127584 | Periplasmic superoxide dismutase [Cu-Zn] SodC |
| M. tuberculosis | Rv0440 | OG5_126788 | 60 kDa chaperonin 2 GroEL2 (protein CPN60-2) (GroEL protein 2) (65 kDa antigen) ... |
| M. tuberculosis | Rv0444c | OG5_170946 | Anti-sigma factor RskA (regulator of sigma K) |
| M. tuberculosis | Rv0445c | OG5_140515 | Alternative RNA polymerase sigma factor SigK |
| M. tuberculosis | Rv0447c | OG5_127897 | Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty ... |
| M. tuberculosis | Rv0453 | OG5_197815 | PPE family protein PPE11 |
| M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) |
| M. tuberculosis | Rv0469 | OG5_132295 | Possible mycolic acid synthase UmaA |
| M. tuberculosis | Rv0470c | OG5_208994 | Mycolic acid synthase PcaA (cyclopropane synthase) |
| M. tuberculosis | Rv0482 | OG5_131886 | Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramat ... |
| M. tuberculosis | Rv0491 | OG5_131511 | Two component sensory transduction protein RegX3 (transcriptional regulatory pro ... |