Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
783 records found | Showing page 18 of 32 (records 426-450) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0436c | OG5_129764 | Probable CDP-diacylglycerol--serine O-phosphatidyltransferase PssA (PS synthase) ... |
| M. tuberculosis | Rv0936 | OG5_131047 | Phosphate-transport integral membrane ABC transporter PstA2 |
| M. tuberculosis | Rv0933 | OG5_130152 | Phosphate-transport ATP-binding protein ABC transporter PstB |
| M. tuberculosis | Rv0153c | OG5_132308 | Phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase) (PTPase) |
| M. tuberculosis | Rv0781 | OG5_129295 | Probable protease II PtrBa [first part] (oligopeptidase B) |
| M. tuberculosis | Rv0357c | OG5_127011 | Probable adenylosuccinate synthetase PurA (imp--aspartate ligase) (ADSS) (ampsas ... |
| M. tuberculosis | Rv0780 | OG5_131443 | Phosphoribosylaminoimidazole- succinocarboxamide synthase PurC (SAICAR synthetas ... |
| M. tuberculosis | Rv3275c | OG5_127668 | Probable phosphoribosylaminoimidazole carboxylase catalytic subunit PurE (air ca ... |
| M. tuberculosis | Rv0957 | OG5_127961 | Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimida ... |
| M. tuberculosis | Rv0809 | OG5_126894 | Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribo ... |
| M. tuberculosis | Rv2964 | OG5_131386 | Probable formyltetrahydrofolate deformylase PurU (formyl-FH(4) hydrolase) |
| M. tuberculosis | Rv2883c | OG5_130032 | Probable uridylate kinase PyrH (UK) (uridine monophosphate kinase) (UMP kinase) |
| M. tuberculosis | Rv2195 | OG5_196282 | Probable rieske iron-sulfur protein QcrA |
| M. tuberculosis | Rv2196 | OG5_128504 | Probable ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) |
| M. tuberculosis | Rv2737c | OG5_130095 | RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. |
| M. tuberculosis | Rv0630c | OG5_140510 | Probable exonuclease V (beta chain) RecB (exodeoxyribonuclease V beta chain)(exo ... |
| M. tuberculosis | Rv0631c | OG5_141789 | Probable exonuclease V (gamma chain) RecC (exodeoxyribonuclease V gamma chain)(e ... |
| M. tuberculosis | Rv3783 | OG5_136920 | Probable O-antigen/lipopolysaccharide transport integral membrane protein ABC tr ... |
| M. tuberculosis | Rv3211 | OG5_128505 | Probable ATP-dependent RNA helicase RhlE |
| M. tuberculosis | Rv1940 | No group | Probable riboflavin biosynthesis protein RibA1 (GTP cyclohydrolase II) |
| M. tuberculosis | Rv1415 | OG5_127275 | Probable riboflavin biosynthesis protein RibA2 : GTP cyclohydrolase II + 3,4-dih ... |
| M. tuberculosis | Rv1412 | OG5_129511 | Probable riboflavin synthase alpha chain RibC (RibE) |
| M. tuberculosis | Rv0334 | OG5_131815 | Alpha-D-glucose-1-phosphate thymidylyltransferase RmlA (dTDP-glucose synthase) ( ... |
| M. tuberculosis | Rv3464 | OG5_127949 | dTDP-glucose 4,6-dehydratase RmlB |
| M. tuberculosis | Rv3465 | OG5_132926 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (dTDP-4-keto-6-deoxyglucose 3,5-epimer ... |