Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2584 records found | Showing page 63 of 104 (records 1551-1575) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv2349c | OG5_131170 | Probable phospholipase C 3 PlcC |
| M. tuberculosis | Rv2350c | OG5_131170 | Membrane-associated phospholipase C 2 PlcB |
| M. tuberculosis | Rv2351c | OG5_131170 | Membrane-associated phospholipase C 1 PlcA (MTP40 antigen) |
| M. tuberculosis | Rv2352c | OG5_135481 | PPE family protein PPE38 |
| M. tuberculosis | Rv2353c | OG5_132376 | PPE family protein PPE39 |
| M. tuberculosis | Rv2354 | OG5_131793 | PROBABLE TRANSPOSASE FOR INSERTION SEQUENCE ELEMENT IS6110 (FRAGMENT) |
| M. tuberculosis | Rv2355 | OG5_128670 | Probable transposase |
| M. tuberculosis | Rv2356c | OG5_132376 | PPE family protein PPE40 |
| M. tuberculosis | Rv2358 | OG5_155588 | Probable transcriptional regulatory protein SmtB (probably ArsR-family) |
| M. tuberculosis | Rv2359 | OG5_130371 | Probable zinc uptake regulation protein Zur |
| M. tuberculosis | Rv2362c | OG5_143159 | Possible DNA repair protein RecO |
| M. tuberculosis | Rv2363 | OG5_141344 | Probable amidase AmiA2 (aminohydrolase) |
| M. tuberculosis | Rv2365c | OG5_237599 | Conserved hypothetical protein |
| M. tuberculosis | Rv2368c | OG5_133737 | Probable PHOH-like protein PhoH1 (phosphate starvation-inducible protein PSIH) |
| M. tuberculosis | Rv2370c | OG5_239136 | Conserved hypothetical protein |
| M. tuberculosis | Rv2371 | No group | PE-PGRS family protein PE_PGRS40 |
| M. tuberculosis | Rv2372c | OG5_131160 | Conserved hypothetical protein |
| M. tuberculosis | Rv2374c | OG5_136231 | Probable heat shock protein transcriptional repressor HrcA |
| M. tuberculosis | Rv2376c | OG5_237598 | Low molecular weight antigen CFP2 (low molecular weight protein antigen 2) (CFP- ... |
| M. tuberculosis | Rv2377c | OG5_160502 | Putative conserved protein MbtH |
| M. tuberculosis | Rv2382c | No group | Polyketide synthetase MbtC (polyketide synthase) |
| M. tuberculosis | Rv2383c | OG5_149413 | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) |
| M. tuberculosis | Rv2384 | OG5_146698 | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP s ... |
| M. tuberculosis | Rv2385 | OG5_131762 | Putative acetyl hydrolase MbtJ |
| M. tuberculosis | Rv2386c | OG5_169356 | Isochorismate synthase MbtI |