Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 3 of 9 (records 51-75) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv0234c | OG5_127004 | Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 |
M. tuberculosis | Rv0620 | OG5_129789 | Probable galactokinase GalK (galactose kinase) |
M. tuberculosis | Rv0993 | OG5_131936 | UTP--glucose-1-phosphate uridylyltransferase GalU (UDP-glucose pyrophosphorylase ... |
M. tuberculosis | Rv0112 | OG5_149659 | Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase) |
M. tuberculosis | Rv3809c | OG5_139595 | UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleoti ... |
M. tuberculosis | Rv1326c | OG5_127579 | 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) |
M. tuberculosis | Rv3858c | OG5_126892 | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate syn ... |
M. tuberculosis | Rv3411c | OG5_126887 | Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosi ... |
M. tuberculosis | Rv0005 | OG5_128755 | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ... |
M. tuberculosis | Rv0524 | OG5_129427 | Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semial ... |
M. tuberculosis | Rv1485 | OG5_127510 | Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase) |
M. tuberculosis | Rv1601 | OG5_129258 | Probable imidazole glycerol-phosphate dehydratase HisB |
M. tuberculosis | Rv2121c | OG5_129102 | ATP phosphoribosyltransferase HisG |
M. tuberculosis | Rv1606 | OG5_131046 | Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI |
M. tuberculosis | Rv2299c | OG5_126623 | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (hig ... |
M. tuberculosis | Rv3001c | OG5_129100 | Probable KETOL-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) ( ... |
M. tuberculosis | Rv0189c | OG5_128618 | Probable dihydroxy-acid dehydratase IlvD (dad) |
M. tuberculosis | Rv2210c | OG5_126731 | Branched-chain amino acid transaminase IlvE |
M. tuberculosis | Rv1484 | OG5_130466 | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl ... |
M. tuberculosis | Rv0341 | OG5_146536 | Isoniazid inductible gene protein IniB |
M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
M. tuberculosis | Rv1027c | OG5_136090 | Probable transcriptional regulatory protein KdpE |
M. tuberculosis | Rv2965c | OG5_132912 | Probable phosphopantetheine adenylyltransferase KdtB (pantetheine- phosphate ade ... |
M. tuberculosis | Rv2995c | OG5_126870 | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3 ... |
M. tuberculosis | Rv2987c | OG5_130205 | Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate iso ... |