Target list

Search results for query: T. cruzi ranked list of targets

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  • Score for genes in query #24 (significant druggability): 30
  • Score for genes in query #27 (single copy gene): 20
  • Score for genes in query #26 (ortholog in T. brucei): 20
  • Score for genes in query #23 (not in human): 40
  • Score for genes in query #28 (strucural model available): 15
  • Score for genes in query #22 (enzyme): 30
  • Score for genes in query #25 (essentiality evidence in any specie): 20
  • Score for genes in query #29 (assayable): 15

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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18619 records found | Showing page 4 of 745 (records 76-100) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.509151.40   OG5_136758   inorganic polyphosphate/ATP-NAD kinase, putative 140
T. cruzi   TcCLB.504153.160   OG5_132183   metallo-peptidase, Clan MA(E) Family M32 140
T. cruzi   TcCLB.511283.280   OG5_127026   Serine/threonine-protein kinase NEK16, putative 140
T. cruzi   TcCLB.503849.60   OG5_128620   NADH-dependent fumarate reductase, putative 140
T. cruzi   TcCLB.509151.130   OG5_143192   deoxyuridine triphosphatase, putative 140
T. cruzi   TcCLB.508717.20   OG5_126960   NADH dehydrogenase, putative 140
T. cruzi   TcCLB.507829.10   OG5_148485   cysteine peptidase, Clan CA, family C2, putative 140
T. cruzi   TcCLB.503855.40   OG5_135138   calpain-like cysteine peptidase, putative 140
T. cruzi   TcCLB.503685.10   OG5_153007   serine/threonine-protein kinase, putative 140
T. cruzi   TcCLB.508441.20   OG5_128435   Phosphoenolpyruvate carboxykinase [ATP], glycosomal 140
T. cruzi   TcCLB.511269.70   OG5_148485   cysteine peptidase, Clan CA, family C2, putative 140
T. cruzi   TcCLB.507547.90   OG5_128435   glycosomal protein P60 140
T. cruzi   TcCLB.509029.10   OG5_138572   serine/threonine protein phosphatase, putative 140
T. cruzi   TcCLB.510141.10   OG5_126909   thymine-7-hydroxylase, putative 140
T. cruzi   TcCLB.503513.10   OG5_143898   casein kinase II, alpha chain, putative 140
T. cruzi   TcCLB.508375.30   OG5_128535   aspartate carbamoyltransferase, putative 140
T. cruzi   TcCLB.509875.170   OG5_150015   pyruvate dehydrogenase (lipoamide) kinase, putative 140
T. cruzi   TcCLB.507059.60   OG5_126793   orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 140
T. cruzi   TcCLB.503581.20   OG5_148443   peptidyl-prolyl cis-trans isomerase, putative 140
T. cruzi   TcCLB.507019.20   OG5_144738   nitrate reductase, putative 140
T. cruzi   TcCLB.504013.110   OG5_137674   Serine/threonine-protein phosphatase 2A catalytic subunit, putative 140
T. cruzi   TcCLB.506839.70   OG5_126960   NADH dehydrogenase, putative 140
T. cruzi   TcCLB.509733.180   OG5_138748   adenylate kinase, putative 140
T. cruzi   TcCLB.510879.80   OG5_128713   serine acetyltransferase, putative 140
T. cruzi   TcCLB.511491.100   OG5_136796   phosphatase 2C, putative 140

Showing page 4 (records 76-100) of 745