Target list

Search results for query: T. cruzi ranked list of targets

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  • Score for genes in query #25 (essentiality evidence in any specie): 20
  • Score for genes in query #28 (strucural model available): 15
  • Score for genes in query #24 (significant druggability): 30
  • Score for genes in query #22 (enzyme): 30
  • Score for genes in query #29 (assayable): 15
  • Score for genes in query #27 (single copy gene): 20
  • Score for genes in query #26 (ortholog in T. brucei): 20
  • Score for genes in query #23 (not in human): 40

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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18619 records found | Showing page 3 of 745 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.510663.80   OG5_130463   Tetrapyrrole (Corrin/Porphyrin) Methylases, putative 145
T. cruzi   TcCLB.507913.20   OG5_131773   phosphomevalonate kinase protein, putative 145
T. cruzi   TcCLB.509779.60   OG5_141243   dual-specificity protein phosphatase, putative 145
T. cruzi   TcCLB.511391.120   OG5_127974   metallo-peptidase, clan MH, family M18, putative 145
T. cruzi   TcCLB.506801.110   OG5_128882   folate-binding protein YgfZ, putative 145
T. cruzi   TcCLB.507005.4   OG5_146285   acyl transferase-like protein 145
T. cruzi   TcCLB.509167.150   OG5_129171   homoserine kinase 145
T. cruzi   TcCLB.507867.70   OG5_127549   prefoldin subunit, putative 145
T. cruzi   TcCLB.510187.400   OG5_151863   serine/threonine protein phosphatase, putative 140
T. cruzi   TcCLB.507757.70   OG5_138783   dihydrolipoamide dehydrogenase, putative 140
T. cruzi   TcCLB.508153.400   OG5_144700   Serine/threonine-protein kinase NEK7, putative 140
T. cruzi   TcCLB.506819.30   OG5_153133   superoxide dismutase, putative 140
T. cruzi   TcCLB.510323.10   OG5_154473   protein kinase, putative 140
T. cruzi   TcCLB.505843.10   OG5_130284   glutamate dehydrogenase, putative 140
T. cruzi   TcCLB.508175.260   OG5_136758   poly(p)/ATP NAD kinase, putative 140
T. cruzi   TcCLB.511127.400   OG5_138572   serine/threonine protein phosphatase, putative 140
T. cruzi   TcCLB.508409.160   OG5_126909   thymine-7-hydroxylase, putative 140
T. cruzi   TcCLB.508175.160   OG5_143192   deoxyuridine triphosphatase, putative 140
T. cruzi   TcCLB.506513.110   OG5_134039   peptidase t, putative 140
T. cruzi   TcCLB.508153.510   OG5_150111   Serine/threonine-protein kinase NEK6, putative 140
T. cruzi   TcCLB.509033.30   OG5_148842   cyclophilin, putative 140
T. cruzi   TcCLB.504797.100   OG5_133785   rotamase, putative 140
T. cruzi   TcCLB.508405.70   OG5_136478   protein kinase, putative 140
T. cruzi   TcCLB.506697.30   OG5_150111   Serine/threonine-protein kinase NEK6, putative 140
T. cruzi   TcCLB.508999.190   OG5_135138   cysteine peptidase, Clan CA, family C2, putative 140

Showing page 3 (records 51-75) of 745