Target list

Search results for query: Pfal rankings for 19 criteria -- reweightable!

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #298 (Pfal late schizont 80-100): 8
  • Score for genes in query #315 (Pfal compound desirability > 0.3): 35
  • Score for genes in query #305 (Pfal not in humans): 25
  • Score for genes in query #310 (Pfal late trophozoite 80-100): 8
  • Score for genes in query #294 (Pfal early schizont 80-100): 8
  • Score for genes in query #296 (Pfal early ring 60-80): 4
  • Score for genes in query #301 (Pfal enzymes): 100
  • Score for genes in query #316 (Pfal early schizont 60-80): 4
  • Score for genes in query #312 (Pfal merozoite 60-80): 4
  • Score for genes in query #309 (Pfal no TM domains): 20
  • Score for genes in query #303 (Pfal PDB structures): 50
  • Score for genes in query #293 (Pfal late schizont 60-80): 4
  • Score for genes in query #307 (Pfal genetic validation): 50
  • Score for genes in query #311 (Pfal druggability > 0.6): 35
  • Score for genes in query #297 (Pfal early ring 80-100): 8
  • Score for genes in query #308 (Pfal early trophozoite 60-80): 4
  • Score for genes in query #302 (Pfal structural models): 30
  • Score for genes in query #299 (Pfal essential in at least one organism): 40
  • Score for genes in query #313 (Pfal less than 100 kDa): 20
  • Score for genes in query #304 (Pfal late trophozoite 60-80): 4
  • Score for genes in query #292 (Pfal merozoite 80-100): 8
  • Score for genes in query #306 (Pfal late ring 80-100): 8
  • Score for genes in query #300 (Pfal publications): 35
  • Score for genes in query #314 (Pfal late ring 60-80): 4
  • Score for genes in query #295 (Pfal early trophozoite 80-100): 8
  • Score for genes in query #291 (Pfal assayable): 30

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 192 of 193 (records 4776-4800) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1212600   OG5_144736   conserved protein, unknown function, unspecified product 45
P. falciparum   PF3D7_1214800   OG5_173913   conserved Plasmodium protein, unknown function 45
P. falciparum   PF3D7_1219800   OG5_205417   conserved Plasmodium protein, unknown function 45
P. falciparum   PF3D7_1233800   OG5_147418   conserved Plasmodium protein, unknown function 45
P. falciparum   PF3D7_1251100   OG5_173920   conserved Plasmodium protein, unknown function 45
P. falciparum   PF3D7_1321400   OG5_156178   palmitoyltransferase DHHC8, putative 44
P. falciparum   PF3D7_0903100   OG5_127650   protein RER1, putative 44
P. falciparum   PF3D7_1143800   OG5_128466   conserved Plasmodium protein, unknown function 42
P. falciparum   PF3D7_1366100   OG5_130151   DIP13 homolog, putative 40
P. falciparum   PF3D7_1355800   OG5_128788   splicing factor 3B subunit 5, putative 40
P. falciparum   PF3D7_1459300   OG5_129238   OPA3-like protein, putative 40
P. falciparum   PF3D7_1462500   OG5_160996   conserved Plasmodium protein, unknown function 40
P. falciparum   PF3D7_1470000   OG5_130185   autophagy-related protein 12, putative 40
P. falciparum   PF3D7_0205800   OG5_135658   PH domain-containing protein, putative 40
P. falciparum   PF3D7_0604200   OG5_143072   mitochondrial ribosomal protein L41, putative 40
P. falciparum   PF3D7_0904500   OG5_128513   prefoldin subunit 4, putative 40
P. falciparum   PF3D7_1225700   OG5_128499   VAC14 domain-containing protein, putative 34
P. falciparum   PF3D7_1121000   OG5_129316   palmitoyltransferase DHHC3 32
P. falciparum   PF3D7_1358000   OG5_163078   patatin-like phospholipase, putative 30
P. falciparum   PF3D7_0806200   OG5_131282   C-mannosyltransferase, putative 30
P. falciparum   PF3D7_0613300   OG5_133090   rhoptry protein ROP14 30
P. falciparum   PF3D7_0918400   OG5_167149   conserved Plasmodium protein, unknown function 25
P. falciparum   PF3D7_0932700   OG5_159755   conserved Plasmodium protein, unknown function 25
P. falciparum   PF3D7_0526900   OG5_127696   transmembrane emp24 domain-containing protein, putative 24
P. falciparum   PF3D7_1340800   OG5_128371   mitochondrial pyruvate carrier protein 1, putative 20

Showing page 192 (records 4776-4800) of 193