You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs
Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8205 records found | Showing page 1 of 329 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
L. major | LmjF.29.0820 | OG5_127800 | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin ... | 445 |
L. major | LmjF.36.0550 | OG5_126712 | cell division related protein kinase 2,cdc2-related kinase | 415 |
L. major | LmjF.23.0050 | OG5_126792 | cyclophilin 11, putative | 415 |
L. major | LmjF.05.0350 | OG5_126785 | trypanothione reductase | 415 |
L. major | LmjF.06.0120 | OG5_127452 | cyclophilin 2 | 415 |
L. major | LmjF.25.0910 | OG5_126792 | cyclophilin a | 415 |
L. major | LmjF.18.0270 | OG5_126888 | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 415 |
L. major | LmjF.06.0860 | OG5_127385 | dihydrofolate reductase-thymidylate synthase | 415 |
L. major | LmjF.36.1960 | OG5_127648 | phosphomannomutase, putative | 395 |
L. major | LmjF.24.0850 | OG5_127002 | triosephosphate isomerase | 380 |
L. major | LmjF.13.0390 | OG5_126605 | alpha tubulin | 380 |
L. major | LmjF.21.1080 | OG5_126712 | cell division protein kinase 2,cdc2-related kinase | 380 |
L. major | LmjF.19.1440 | OG5_126781 | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 380 |
L. major | LmjF.30.2970 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 380 |
L. major | LmjF.08.1080 | OG5_126607 | cathepsin L-like protease | 375 |
L. major | LmjF.08.1060 | OG5_126607 | cathepsin L-like protease | 375 |
L. major | LmjF.08.1030 | OG5_126607 | cathepsin L-like protease | 375 |
L. major | LmjF.34.1260 | OG5_127218 | mitochondrial DNA polymerase I protein A, putative | 365 |
L. major | LmjF.22.1360 | OG5_127590 | farnesyl pyrophosphate synthase | 365 |
L. major | LmjF.31.2940 | OG5_129470 | squalene synthase, putative | 365 |
L. major | LmjF.28.2430 | OG5_127061 | vacuolar ATP synthase subunit b, putative | 365 |
L. major | LmjF.33.1630 | OG5_126792 | cyclophilin 4, putative | 365 |
L. major | LmjF.19.0550 | OG5_126721 | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 365 |
L. major | LmjF.32.1580 | OG5_127555 | phosphomannose isomerase | 365 |
L. major | LmjF.30.0880 | OG5_128398 | adenosine kinase, putative | 365 |