Target list

Search results for query: Reweightable Leish rankings (12 criteria)

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  • Score for genes in query #338 (Leish < 100 kDa): 20
  • Score for genes in query #347 (Leish compound desirability > 0.3): 35
  • Score for genes in query #348 (Leish PubMed publications): 35
  • Score for genes in query #346 (Leish druggability > 0.6): 35
  • Score for genes in query #337 (Leish enzymes): 100
  • Score for genes in query #342 (Leish present in all TriTryps): 25
  • Score for genes in query #341 (Leish structural model (ModBase)): 30
  • Score for genes in query #339 (Leish no transmembrane domains): 20
  • Score for genes in query #344 (Leish essential): 40
  • Score for genes in query #343 (Leish not in humans): 25
  • Score for genes in query #340 (Leish PDB structure): 50
  • Score for genes in query #345 (Leish genetic validation): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8205 records found | Showing page 3 of 329 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.31.0560   OG5_128331   mevalonate kinase, putative 345
L. major   LmjF.30.2980   OG5_126628   glyceraldehyde 3-phosphate dehydrogenase, glycosomal 345
L. major   LmjF.26.0140   OG5_127379   adenine phosphoribosyltransferase 345
L. major   LmjF.12.0530   OG5_126980   glucose-6-phosphate isomerase 345
L. major   LmjF.35.0020   OG5_126685   pyruvate kinase 345
L. major   LmjF.16.1540   OG5_128177   DNA polymerase I alpha catalytic subunit, putative 345
L. major   LmjF.16.0530   OG5_127289   dihydroorotate dehydrogenase 340
L. major   LmjF.12.0220   OG5_127291   hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 340
L. major   LmjF.30.3520   OG5_126734   S-adenosylmethionine synthetase 330
L. major   LmjF.21.0240   OG5_126743   hexokinase, putative 330
L. major   LmjF.35.1010   OG5_126780   casein kinase, putative 330
L. major   LmjF.32.0870   OG5_127036   phenylalanyl-tRNA synthetase alpha chain, putative 330
L. major   LmjF.27.0250   OG5_127472   flap endonuclease-1 (FEN-1), putative 330
L. major   LmjF.19.1560   OG5_126887   inosine-5-monophosphate dehydrogenase 330
L. major   LmjF.22.0110   OG5_127152   GMP synthase, putative,glutamine amidotransferase, putative 330
L. major   LmjF.17.0360   OG5_127381   cytidine deaminase-like protein 330
L. major   LmjF.21.0680   OG5_126742   histone deacetylase, putative 330
L. major   LmjF.18.1080   OG5_126748   protein kinase A catalytic subunit 330
L. major   LmjF.24.2110   OG5_127526   hypothetical protein, conserved 330
L. major   LmjF.18.1220   OG5_127154   prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putativ ... 330
L. major   LmjF.28.0690   OG5_126821   serine/threonine protein phosphatase catalytic subunit, putative 330
L. major   LmjF.27.2410   OG5_126583   aldo-keto reductase-like protein 330
L. major   LmjF.06.0370   OG5_127569   glutamine synthetase, putative 330
L. major   LmjF.21.0810   OG5_127468   methionyl-tRNA synthetase, putative 330
L. major   LmjF.18.0020   OG5_128252   mevalonate-diphosphate decarboxylase, putative 330

Showing page 3 (records 51-75) of 329