Target list

Search results for query: Reweightable Leish rankings (12 criteria)

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  • Score for genes in query #339 (Leish no transmembrane domains): 20
  • Score for genes in query #340 (Leish PDB structure): 50
  • Score for genes in query #345 (Leish genetic validation): 50
  • Score for genes in query #338 (Leish < 100 kDa): 20
  • Score for genes in query #343 (Leish not in humans): 25
  • Score for genes in query #348 (Leish PubMed publications): 35
  • Score for genes in query #341 (Leish structural model (ModBase)): 30
  • Score for genes in query #342 (Leish present in all TriTryps): 25
  • Score for genes in query #347 (Leish compound desirability > 0.3): 35
  • Score for genes in query #337 (Leish enzymes): 100
  • Score for genes in query #344 (Leish essential): 40
  • Score for genes in query #346 (Leish druggability > 0.6): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8205 records found | Showing page 2 of 329 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.21.0250   OG5_126743   hexokinase, putative 365
L. major   LmjF.11.1100   OG5_129288   lanosterol 14-alpha-demethylase, putative 365
L. major   LmjF.25.1320   OG5_127141   serine/threonine protein phosphatase, putative 365
L. major   LmjF.21.1210   OG5_129576   thymidine kinase, putative 365
L. major   LmjF.08.1010   OG5_126607   cathepsin L-like protease 355
L. major   LmjF.19.1420   OG5_126607   cysteine peptidase A (CPA) 355
L. major   LmjF.13.0360   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0320   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0300   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0330   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0290   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0310   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0280   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0350   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0340   OG5_126605   alpha tubulin 350
L. major   LmjF.13.0370   OG5_126605   alpha tubulin 350
L. major   LmjF.36.1260   OG5_127143   fructose-1,6-bisphosphate aldolase 345
L. major   LmjF.32.0080   OG5_127597   N-myristoyl transferase, putative 345
L. major   LmjF.28.2280   OG5_127113   DNA topoisomerase ii 345
L. major   LmjF.23.0110   OG5_127109   GDP-mannose pyrophosphorylase 345
L. major   LmjF.20.0100   OG5_126776   phosphoglycerate kinase C, glycosomal 345
L. major   LmjF.33.1690   OG5_127429   DNA polymerase delta catalytic subunit, putative 345
L. major   LmjF.18.0990   OG5_128034   UDP-glucose pyrophosphorylase 345
L. major   LmjF.18.0090   OG5_126880   alpha glucosidase II subunit, putative 345
L. major   LmjF.35.0030   OG5_126685   pyruvate kinase 345

Showing page 2 (records 26-50) of 329