Target list

Search results for query: Union of (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #13 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #12 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #8 (any essentiality evidence): 3
  • Score for genes in query #17 (Caffrey et al 's TOP 35): 0
  • Score for genes in query #1 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #6 (Morphology Defect in C. elegans): 3
  • Score for genes in query #15 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #16 (Caffrey et al 's TOP 18): 0
  • Score for genes in query #9 (in human): -20
  • Score for genes in query #3 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #7 (Sterility in C. elegans): 3
  • Score for genes in query #4 (Growth Defect in C. elegans): 3
  • Score for genes in query #2 (Orthologs of D. melanogaster genes with mutant phenotype "neurophysiological defect"): 10
  • Score for genes in query #14 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #11 (druggable genes inferred by sequence simiarity): 20
  • Score for genes in query #10 (structural model available): 10
  • Score for genes in query #5 (Larval/Adult Lethal/Arrest in C. elegans): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

10633 records found | Showing page 425 of 426 (records 10601-10625) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_142230   OG5_131579   cd63 antigen-like -20
S. mansoni   Smp_098570   OG5_128996   sodium-bile acid cotransporter -20
S. mansoni   Smp_006240   OG5_131959   hypothetical protein -20
S. mansoni   Smp_171250   OG5_130704   hypothetical protein -20
S. mansoni   Smp_042740   OG5_130233   spag6 -20
S. mansoni   Smp_161570   OG5_173345   hypothetical protein -20
S. mansoni   Smp_115470   OG5_128385   exportin 7-related / ran binding protein 1617 -20
S. mansoni   Smp_174700   OG5_131038   hepatocyte nuclear factor 4-alpha (hnf-4-alpha) -20
S. mansoni   Smp_178690   OG5_137140   hypothetical protein -20
S. mansoni   Smp_152390   OG5_134292   hypothetical protein -20
S. mansoni   Smp_165430   OG5_135202   hypothetical protein -20
S. mansoni   Smp_114200   OG5_130853   hypothetical protein -20
S. mansoni   Smp_096910   OG5_130031   dolichyl glycosyltransferase -20
S. mansoni   Smp_150730   OG5_155035   discoidin domain receptor -20
S. mansoni   Smp_073990   OG5_129044   hypothetical protein -20
S. mansoni   Smp_184530   OG5_130637   nucleic acid binding protein -20
S. mansoni   Smp_188420   OG5_149418   hypothetical protein -20
S. mansoni   Smp_036660     No group hypothetical protein -20
S. mansoni   Smp_045680   OG5_198770   sodium/hydrogen exchanger 3 (nhe3) -20
S. mansoni   Smp_116570   OG5_242240   hypothetical protein -20
S. mansoni   Smp_152220   OG5_127824   hypothetical protein -20
S. mansoni   Smp_022540.1   OG5_131222   hypothetical protein -20
S. mansoni   Smp_060210   OG5_128409   lipopolysaccharide-induced transcription factor regulating tumor necrosis factor ... -20
S. mansoni   Smp_145070   OG5_229746   asparagine-rich antigen -20
S. mansoni   Smp_010720   OG5_205421   elongation of fatty acids protein 1 -20

Showing page 425 (records 10601-10625) of 426