Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 3 of 91 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product | Weight |
|---|---|---|---|---|
| M. tuberculosis | Rv1259 | OG5_149670 | Probable uracil DNA glycosylase, UdgB | 13 |
| M. tuberculosis | Rv1580c | No group | Probable PhiRv1 phage protein | 13 |
| M. tuberculosis | Rv1780 | OG5_237692 | Conserved protein | 13 |
| M. tuberculosis | Rv3173c | OG5_171043 | Probable transcriptional regulatory protein (probably TetR/AcrR-family) | 13 |
| M. tuberculosis | Rv3677c | OG5_129461 | Possible hydrolase | 13 |
| M. tuberculosis | Rv1613 | OG5_130207 | Probable tryptophan synthase, alpha subunit TrpA | 13 |
| M. tuberculosis | Rv0346c | OG5_127087 | Possible L-asparagine permease AnsP2 (L-asparagine transport protein) | 12 |
| M. tuberculosis | Rv2376c | OG5_237598 | Low molecular weight antigen CFP2 (low molecular weight protein antigen 2) (CFP- ... | 12 |
| M. tuberculosis | Rv2995c | OG5_126870 | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3 ... | 12 |
| M. tuberculosis | Rv3523 | OG5_168800 | Probable lipid carrier protein or keto acyl-CoA thiolase Ltp3 | 12 |
| M. tuberculosis | Rv1283c | OG5_128014 | Probable oligopeptide-transport integral membrane protein ABC transporter OppB | 12 |
| M. tuberculosis | Rv3507 | OG5_129879 | PE-PGRS family protein PE_PGRS53 | 12 |
| M. tuberculosis | Rv0532 | OG5_129879 | PE-PGRS family protein PE_PGRS6 | 12 |
| M. tuberculosis | Rv0125 | OG5_171368 | Probable serine protease PepA (serine proteinase) (MTB32A) | 12 |
| M. tuberculosis | Rv1705c | OG5_135481 | PPE family protein PPE22 | 12 |
| M. tuberculosis | Rv0008c | No group | Possible membrane protein | 12 |
| M. tuberculosis | Rv0139 | OG5_136762 | Possible oxidoreductase | 12 |
| M. tuberculosis | Rv0295c | No group | Conserved protein | 12 |
| M. tuberculosis | Rv0792c | OG5_134860 | Probable transcriptional regulatory protein (probably GntR-family) | 12 |
| M. tuberculosis | Rv0914c | OG5_128557 | Possible lipid carrier protein or keto acyl-CoA thiolase | 12 |
| M. tuberculosis | Rv1587c | OG5_151920 | Partial REP13E12 repeat protein | 12 |
| M. tuberculosis | Rv1721c | No group | Possible antitoxin VapB12 | 12 |
| M. tuberculosis | Rv2021c | OG5_239151 | Transcriptional regulatory protein | 12 |
| M. tuberculosis | Rv2036 | OG5_239152 | Conserved hypothetical protein | 12 |
| M. tuberculosis | Rv2419c | OG5_135095 | Glucosyl-3-phosphoglycerate phosphatase GpgP | 12 |