Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
394 records found | Showing page 15 of 16 (records 351-375) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3465 | OG5_132926 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (dTDP-4-keto-6-deoxyglucose 3,5-epimer ... |
| M. tuberculosis | Rv3469c | OG5_155516 | Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA) |
| M. tuberculosis | Rv3490 | OG5_129327 | Alpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA (trehalose-6-phosph ... |
| M. tuberculosis | Rv3506 | OG5_239145 | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligas ... |
| M. tuberculosis | Rv3513c | OG5_239171 | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FA ... |
| M. tuberculosis | Rv3534c | OG5_155516 | Probable 4-hydroxy-2-oxovalerate aldolase (HOA) |
| M. tuberculosis | Rv3546 | No group | Probable acetyl-CoA acetyltransferase FadA5 (acetoacetyl-CoA thiolase) |
| M. tuberculosis | Rv3550 | No group | Probable enoyl-CoA hydratase EchA20 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv3556c | OG5_147360 | Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase) |
| M. tuberculosis | Rv3566c | OG5_131280 | Arylamine N-acetyltransferase Nat (arylamine acetylase) |
| M. tuberculosis | Rv3579c | OG5_128345 | Possible tRNA/rRNA methyltransferase |
| M. tuberculosis | Rv3589 | OG5_128159 | Probable adenine glycosylase MutY |
| M. tuberculosis | Rv3601c | OG5_134769 | Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase ... |
| M. tuberculosis | Rv3602c | OG5_129569 | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activatin ... |
| M. tuberculosis | Rv3607c | OG5_133572 | Probable dihydroneopterin aldolase FolB (DHNA) |
| M. tuberculosis | Rv3609c | OG5_127507 | GTP cyclohydrolase I FolE (GTP-ch-I) |
| M. tuberculosis | Rv3610c | OG5_126616 | Membrane-bound protease FtsH (cell division protein) |
| M. tuberculosis | Rv3617 | OG5_129061 | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv3670 | OG5_130074 | Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv3679 | OG5_208940 | Probable anion transporter ATPase |
| M. tuberculosis | Rv3680 | OG5_175538 | Probable anion transporter ATPase |
| M. tuberculosis | Rv3682 | OG5_208953 | Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 ... |
| M. tuberculosis | Rv3704c | OG5_139531 | Glutamate--cysteine ligase GshA (gamma-glutamylcysteine synthetase) (gamma-ECS) ... |
| M. tuberculosis | Rv3708c | OG5_128664 | Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic s ... |
| M. tuberculosis | Rv3720 | OG5_127897 | Possible fatty acid synthase |