Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 4 of 9 (records 76-100) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv1319c | OG5_176490 | Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) |
| M. tuberculosis | Rv1320c | OG5_176490 | Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) |
| M. tuberculosis | Rv1350 | OG5_126618 | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carri ... |
| M. tuberculosis | Rv1380 | OG5_128535 | Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylas ... |
| M. tuberculosis | Rv1416 | OG5_128902 | Probable riboflavin synthase beta chain RibH (6,7-dimethyl-8-ribityllumazine syn ... |
| M. tuberculosis | Rv1437 | OG5_126776 | Probable phosphoglycerate kinase Pgk |
| M. tuberculosis | Rv1448c | OG5_152385 | Probable transaldolase Tal |
| M. tuberculosis | Rv1484 | OG5_130466 | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl ... |
| M. tuberculosis | Rv1538c | OG5_127035 | Probable L-aparaginase AnsA |
| M. tuberculosis | Rv1552 | OG5_126927 | Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) ... |
| M. tuberculosis | Rv1553 | OG5_126893 | Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) ... |
| M. tuberculosis | Rv1554 | OG5_161648 | Probable fumarate reductase [membrane anchor subunit] FrdC (fumarate dehydrogena ... |
| M. tuberculosis | Rv1555 | OG5_161647 | Probable fumarate reductase [membrane anchor subunit] FrdD (fumarate dehydrogena ... |
| M. tuberculosis | Rv1568 | OG5_128068 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA |
| M. tuberculosis | Rv1695 | OG5_127041 | Inorganic polyphosphate/ATP-NAD kinase PpnK (poly(P)/ATP NAD kinase) |
| M. tuberculosis | Rv1731 | OG5_164857 | Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 |
| M. tuberculosis | Rv1746 | OG5_144303 | Anchored-membrane serine/threonine-protein kinase PknF (protein kinase F) (STPK ... |
| M. tuberculosis | Rv1755c | OG5_131170 | PROBABLE PHOSPHOLIPASE C 4 (FRAGMENT) PLCD |
| M. tuberculosis | Rv1833c | OG5_169867 | Possible haloalkane dehalogenase |
| M. tuberculosis | Rv1837c | OG5_159543 | Malate synthase G GlcB |
| M. tuberculosis | Rv1844c | OG5_127175 | Probable 6-phosphogluconate dehydrogenase Gnd1 |
| M. tuberculosis | Rv1848 | OG5_139588 | Urease gamma subunit UreA (urea amidohydrolase) |
| M. tuberculosis | Rv1849 | OG5_145075 | Urease beta subunit UreB (urea amidohydrolase) |
| M. tuberculosis | Rv1850 | OG5_132452 | Urease alpha subunit UreC (urea amidohydrolase) |
| M. tuberculosis | Rv1854c | OG5_126960 | Probable NADH dehydrogenase Ndh |