Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 3 of 9 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv1018c | OG5_131193 | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU |
| M. tuberculosis | Rv1070c | OG5_128562 | Probable enoyl-CoA hydratase EchA8 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv1082 | OG5_178532 | Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) |
| M. tuberculosis | Rv1098c | OG5_127258 | Probable fumarase Fum (fumarate hydratase) |
| M. tuberculosis | Rv1106c | OG5_133610 | 3-beta-hydroxysteroid dehydrogenase |
| M. tuberculosis | Rv1122 | OG5_127175 | Probable 6-phosphogluconate dehydrogenase, decarboxylating Gnd2 |
| M. tuberculosis | Rv1131 | OG5_128590 | Probable methylcitrate synthase PrpC |
| M. tuberculosis | Rv1141c | OG5_153107 | Probable enoyl-CoA hydratase EchA11 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv1142c | OG5_153107 | Probable enoyl-CoA hydratase EchA10 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv1143 | OG5_131255 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpr ... |
| M. tuberculosis | Rv1170 | OG5_174832 | N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase Ms ... |
| M. tuberculosis | Rv1213 | OG5_135249 | Glucose-1-phosphate adenylyltransferase GlgC (ADP-glucose synthase) (ADP-glucose ... |
| M. tuberculosis | Rv1256c | OG5_132455 | Probable cytochrome P450 130 Cyp130 |
| M. tuberculosis | Rv1284 | OG5_135410 | Beta-carbonic anhydrase |
| M. tuberculosis | Rv1285 | OG5_137554 | Probable sulfate adenylyltransferase subunit 2 CysD |
| M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... |
| M. tuberculosis | Rv1304 | OG5_128903 | Probable ATP synthase a chain AtpB (protein 6) |
| M. tuberculosis | Rv1305 | OG5_126818 | Probable ATP synthase C chain AtpE (lipid-binding protein) (dicyclohexylcarbodii ... |
| M. tuberculosis | Rv1306 | OG5_134191 | Probable ATP synthase B chain AtpF |
| M. tuberculosis | Rv1307 | OG5_134191 | Probable ATP synthase delta chain AtpH |
| M. tuberculosis | Rv1308 | OG5_127165 | Probable ATP synthase alpha chain AtpA |
| M. tuberculosis | Rv1309 | OG5_127077 | Probable ATP synthase gamma chain AtpG |
| M. tuberculosis | Rv1310 | OG5_127099 | Probable ATP synthase beta chain AtpD |
| M. tuberculosis | Rv1311 | OG5_127404 | Probable ATP synthase epsilon chain AtpC |
| M. tuberculosis | Rv1318c | OG5_176490 | Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) |