Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
213 records found | Showing page 9 of 9 (records 201-213) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3602c | OG5_129569 | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activatin ... |
| M. tuberculosis | Rv3628 | OG5_128875 | Inorganic pyrophosphatase Ppa (pyrophosphate phospho-hydrolase) (PPASE) (inorgan ... |
| M. tuberculosis | Rv3670 | OG5_130074 | Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv3708c | OG5_128664 | Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic s ... |
| M. tuberculosis | Rv3731 | No group | Possible ATP-dependent DNA ligase LigC (polydeoxyribonucleotide synthase [ATP]) ... |
| M. tuberculosis | Rv3774 | OG5_129459 | Possible enoyl-CoA hydratase EchA21 (enoyl hydrase) (unsaturated acyl-CoA hydrat ... |
| M. tuberculosis | Rv3790 | OG5_168974 | Decaprenylphosphoryl-beta-D-ribose 2'-oxidase |
| M. tuberculosis | Rv3794 | OG5_166834 | Integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylin ... |
| M. tuberculosis | Rv3808c | OG5_237548 | Bifunctional UDP-galactofuranosyl transferase GlfT2 |
| M. tuberculosis | Rv3809c | OG5_139595 | UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleoti ... |
| M. tuberculosis | Rv3854c | OG5_140305 | Monooxygenase EthA |
| M. tuberculosis | Rv3855 | OG5_191427 | Transcriptional regulatory repressor protein (TetR-family) EthR |
| M. tuberculosis | Rv3913 | OG5_127532 | Probable thioredoxin reductase TrxB2 (TRXR) (TR) |