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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
4804 records found | Showing page 1 of 193 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
P. falciparum | PF3D7_1332600 | OG5_129467 | apurinic/apyrimidinic endonuclease Apn1, putative | 1286 |
P. falciparum | PF3D7_0104400 | OG5_130373 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | 1276 |
P. falciparum | PF3D7_1344800 | OG5_128535 | aspartate carbamoyltransferase | 1261 |
P. falciparum | PF3D7_0716600 | OG5_128800 | cysteine desulfurase | 1261 |
P. falciparum | PF3D7_1022800 | OG5_130276 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase | 1261 |
P. falciparum | PF3D7_0219500 | OG5_128305 | pseudouridine synthase, putative | 1261 |
P. falciparum | PF3D7_1126000 | OG5_126764 | threonine--tRNA ligase | 1256 |
P. falciparum | PF3D7_1406600 | OG5_133657 | ATP-dependent Clp protease regulatory subunit ClpC, putative | 1256 |
P. falciparum | PF3D7_1005000 | OG5_166421 | methionine--tRNA ligase, putative | 1241 |
P. falciparum | PF3D7_0925300 | OG5_128299 | proline--tRNA ligase, putative | 1241 |
P. falciparum | PF3D7_1223300 | OG5_129568 | DNA gyrase subunit A | 1241 |
P. falciparum | PF3D7_0731600 | OG5_136613 | acyl-CoA synthetase | 1236 |
P. falciparum | PF3D7_1037100 | OG5_144357 | pyruvate kinase 2 | 1236 |
P. falciparum | PF3D7_1313400 | OG5_156840 | DEAD box helicase, putative | 1236 |
P. falciparum | PF3D7_1367700 | OG5_126799 | alanine--tRNA ligase | 1236 |
P. falciparum | PF3D7_0215300 | OG5_136613 | acyl-CoA synthetase | 1236 |
P. falciparum | PF3D7_0504200 | OG5_150571 | ATP-dependent RNA helicase DDX27, putative | 1236 |
P. falciparum | PF3D7_0509600 | OG5_126756 | asparagine--tRNA ligase | 1236 |
P. falciparum | PF3D7_1216000 | OG5_126677 | serine--tRNA ligase, putative | 1236 |
P. falciparum | PF3D7_1357200 | OG5_127621 | glutamate--tRNA ligase | 1231 |
P. falciparum | PF3D7_1436800 | OG5_134854 | ATP-dependent Clp protease proteolytic subunit | 1231 |
P. falciparum | PF3D7_1411400 | OG5_127218 | plastid replication-repair enzyme | 1221 |
P. falciparum | PF3D7_0808200 | OG5_133546 | plasmepsin X | 1216 |
P. falciparum | PF3D7_1116700 | OG5_130494 | dipeptidyl aminopeptidase 1 | 1216 |
P. falciparum | PF3D7_0504000 | OG5_127048 | cation transporting P-ATPase | 1216 |