Target list

Search results for query: Union of (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 24)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #12 (Paralogos): -3
  • Score for genes in query #8 (Assayability - Soluble): 5
  • Score for genes in query #6 (Not In Mammals): 11
  • Score for genes in query #13 (GPI): -3
  • Score for genes in query #9 (Pubmed): 7
  • Score for genes in query #15 (EC ): 3
  • Score for genes in query #4 (Essential (-C. elegans)): 23
  • Score for genes in query #5 (Trypanosomatids): 7
  • Score for genes in query #11 (TM): -3
  • Score for genes in query #10 (PM 100kDa): 3
  • Score for genes in query #14 (Signal Peptide): -3
  • Score for genes in query #24 (PiNoDrug4 WARNING: we were unable to find some of the genes in your list!): weighted list
  • Score for genes in query #7 (Assayability - Assay Available): 5

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

18566 records found | Showing page 1 of 743 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.510575.180   OG5_126886   adenylate kinase, putative 1143
T. cruzi   TcCLB.510243.50   OG5_126886   adenylate kinase, putative 1143
T. cruzi   TcCLB.507089.270   OG5_126968   dihydrolipoyl dehydrogenase, putative 1142
T. cruzi   TcCLB.511025.110   OG5_126968   dihydrolipoyl dehydrogenase, putative 1142
T. cruzi   TcCLB.507011.120   OG5_146285   acyl transferase-like protein, putative 1141
T. cruzi   TcCLB.507005.4   OG5_146285   acyl transferase-like protein 1141
T. cruzi   TcCLB.511589.120   OG5_126736   DNA topoisomerase III, putative 1139
T. cruzi   TcCLB.508851.170   OG5_126736   DNA topoisomerase III, putative 1139
T. cruzi   TcCLB.511281.60   OG5_126685   pyruvate kinase 2, putative 1137
T. cruzi   TcCLB.507993.390   OG5_126685   pyruvate kinase 2, putative 1137
T. cruzi   TcCLB.509331.30   OG5_126680   acetyl-CoA synthetase, putative 1133
T. cruzi   TcCLB.504427.110   OG5_126680   acetyl-CoA synthetase, putative 1133
T. cruzi   TcCLB.510029.40   OG5_127419   DNA-directed RNA polymerase III subunit C11, putative 1132
T. cruzi   TcCLB.511231.50   OG5_127412   aminomethyltransferase, mitochondrial, putative 1132
T. cruzi   TcCLB.504069.90   OG5_126700   centromere/microtubule binding protein cbf5, putative 1132
T. cruzi   TcCLB.511145.70   OG5_126700   centromere/microtubule binding protein cbf5, putative 1132
T. cruzi   TcCLB.509453.40   OG5_127691   DNA-directed RNA polymerase I subunit RPB10, putative 1132
T. cruzi   TcCLB.504017.40   OG5_127412   aminomethyltransferase, mitochondrial, putative 1132
T. cruzi   TcCLB.506701.10   OG5_149690   dihydrolipoamide dehydrogenase, putative 1132
T. cruzi   TcCLB.509379.10   OG5_149690   dihydrolipoamide dehydrogenase, putative 1132
T. cruzi   TcCLB.507467.94   OG5_127688   hypothetical protein, conserved 1131
T. cruzi   TcCLB.508355.104   OG5_127688   hypothetical protein, conserved 1131
T. cruzi   TcCLB.510105.20   OG5_127234   exosome complex exonuclease RRP41A 1130
T. cruzi   TcCLB.509715.9   OG5_127234   Ribosomal RNA processing protein 41A 1130
T. cruzi   TcCLB.510337.30   OG5_130883   adenylosuccinate lyase, putative 1129

Showing page 1 (records 1-25) of 743