Target list

Search results for query: Union of (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 24)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #15 (EC ): 3
  • Score for genes in query #14 (Signal Peptide): -3
  • Score for genes in query #5 (Trypanosomatids): 7
  • Score for genes in query #4 (Essential (-C. elegans)): 23
  • Score for genes in query #12 (Paralogos): -3
  • Score for genes in query #8 (Assayability - Soluble): 5
  • Score for genes in query #24 (PiNoDrug4 WARNING: we were unable to find some of the genes in your list!): weighted list
  • Score for genes in query #10 (PM 100kDa): 3
  • Score for genes in query #9 (Pubmed): 7
  • Score for genes in query #13 (GPI): -3
  • Score for genes in query #6 (Not In Mammals): 11
  • Score for genes in query #11 (TM): -3
  • Score for genes in query #7 (Assayability - Assay Available): 5

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

18566 records found | Showing page 2 of 743 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.503855.30   OG5_130883   adenylosuccinate lyase, putative 1129
T. cruzi   TcCLB.503729.10   OG5_128609   protein phosphatase inhibitor, putative 1129
T. cruzi   TcCLB.510863.30   OG5_128609   protein phosphatase inhibitor, putative 1129
T. cruzi   TcCLB.506835.80   OG5_128085   CAS/CSE/importin domain protein, putative 1129
T. cruzi   TcCLB.511291.120   OG5_127419   DNA-directed RNA polymerase III subunit C11, putative 1129
T. cruzi   TcCLB.506945.30   OG5_128085   CAS/CSE/importin domain protein, putative 1129
T. cruzi   TcCLB.510301.10   OG5_127143   fructose-bisphosphate aldolase, glycosomal, putative 1128
T. cruzi   TcCLB.504643.20   OG5_128165   hypothetical protein, conserved 1128
T. cruzi   TcCLB.508387.70   OG5_146303   Mono-functional DNA-alkylating methyl methanesulfonate N-term/CPSF A subunit reg ... 1128
T. cruzi   TcCLB.507089.80   OG5_154964   exosome-associated protein 2, putative 1128
T. cruzi   TcCLB.504085.20   OG5_154964   exosome-associated protein 2, putative 1128
T. cruzi   TcCLB.509161.20   OG5_128165   hypothetical protein, conserved 1128
T. cruzi   TcCLB.503899.130   OG5_126711   glutathione peroxidase-like protein, putative 1127
T. cruzi   TcCLB.508409.160   OG5_126909   thymine-7-hydroxylase, putative 1127
T. cruzi   TcCLB.507801.60   OG5_128187   pre-mRNA splicing factor 19, putative 1127
T. cruzi   TcCLB.507515.10   OG5_126711   glutathione peroxidase-like protein, putative 1127
T. cruzi   TcCLB.509103.10   OG5_128187   pre-mRNA splicing factor 19, putative 1127
T. cruzi   TcCLB.511585.80   OG5_127023   metallo-peptidase, Clan ME, Family M16 1127
T. cruzi   TcCLB.511649.169   OG5_127962   ATP-dependent DEAD/H RNA helicase, putative 1127
T. cruzi   TcCLB.510155.80   OG5_127023   mitochondrial-processing peptidase subunit beta, putative 1127
T. cruzi   TcCLB.508689.20   OG5_144869   eukaryotic translation initiation factor 3 subunit g 1126
T. cruzi   TcCLB.508181.140   OG5_128875   inorganic pyrophosphatase, putative 1126
T. cruzi   TcCLB.510877.150   OG5_144869   Eukaryotic translation initiation factor 3 subunit 4 1126
T. cruzi   TcCLB.508153.820   OG5_128875   inorganic pyrophosphatase, putative 1126
T. cruzi   TcCLB.504017.79   OG5_127272   glycyl-tRNA synthetase, putative 1126