Target list

Search results for query: Weighted ranking of B. malayi targets for PLOS-NTD

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  • Score for genes in query #314 (Bma any EC): 10
  • Score for genes in query #305 (Bma modbase): 2
  • Score for genes in query #304 (Bma - sterile in Cel): 20
  • Score for genes in query #10 (Bma druggable precedence by similarity to starlite targets): 30
  • Score for genes in query #316 (Bma assayable): 5
  • Score for genes in query #308 (Bma - embryonic lethal/arrest in Cel): 30
  • Score for genes in query #309 (Bma - growth defect in Cel): 20
  • Score for genes in query #310 (Bma - larval/adult lethal/arrest in Cel): 40
  • Score for genes in query #307 (Bma in Cel): 10
  • Score for genes in query #312 (Bma any essentiality): 5
  • Score for genes in query #311 (Bma - morphology defect in Cel): 20
  • Score for genes in query #306 (Bma pubmed): 2
  • Score for genes in query #317 (Bma all proteins): 1
  • Score for genes in query #315 (Bma in PDB): 5

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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11305 records found | Showing page 2 of 453 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_51640   OG5_127762   Proteasome A-type and B-type family protein 168
B. malayi   Bm1_32455   OG5_127555   mannose-6-phosphate isomerase, class I family protein 168
B. malayi   Bm1_12875   OG5_126821   Serine/threonine protein phosphatase PP1-beta catalytic subunit 168
B. malayi   Bm1_14125   OG5_127834   proteasome subunit beta type 1 168
B. malayi   Bm1_12165   OG5_127626   methionyl-tRNA synthetase 168
B. malayi   Bm1_38390   OG5_127141   protein phosphatase 2A. 168
B. malayi   Bm1_52850   OG5_127555   mannose-6-phosphate isomerase, class I family protein 168
B. malayi   Bm1_24805   OG5_127761   proteasome subunit beta type 3 168
B. malayi   Bm1_48165   OG5_127233   Adenosylhomocysteinase 168
B. malayi   Bm1_41510   OG5_127162   FAD binding domain containing protein 168
B. malayi   Bm1_22825   OG5_128238   Protein prenyltransferase alpha subunit repeat containing protein 168
B. malayi   Bm1_41940   OG5_126628   Glyceraldehyde 3-phosphate dehydrogenase 168
B. malayi   Bm1_19675   OG5_126821   Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 168
B. malayi   Bm1_45960   OG5_127099   ATP synthase beta chain, mitochondrial precursor, putative 168
B. malayi   Bm1_40505   OG5_127729   ube2i2 protein 160
B. malayi   Bm1_41310   OG5_126677   Sars1 protein 160
B. malayi   Bm1_39250   OG5_126843   protein disulphide isomerase 160
B. malayi   Bm1_28935   OG5_126843   transglutaminase 160
B. malayi   Bm1_39760   OG5_126677   seryl-tRNA synthetase, mitochondrial precursor, putative 160
B. malayi   Bm1_15605   OG5_127944   RuvB-like 1 160
B. malayi   Bm1_29430   OG5_129154   Cytochrome c oxidase polypeptide Vb, mitochondrial precursor 160
B. malayi   Bm1_07670   OG5_127581   cytochrome C-type heme lyase 158
B. malayi   Bm1_19045   OG5_127028   acyl carrier protein, mitochondrial precursor, putative 158
B. malayi   Bm1_39715   OG5_126623   Endoplasmin precursor 158
B. malayi   Bm1_17890   OG5_127832   T-complex protein 1, delta subunit 158

Showing page 2 (records 26-50) of 453