Target list

Search results for query: PLoS NTD Query 2 (L. major)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 4 of 330 (records 76-100) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.36.5380   OG5_126960   NADH dehydrogenase, putative 291
L. major   LmjF.13.0420   OG5_142658   long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty a ... 291
L. major   LmjF.34.0810   OG5_129030   serine/threonine-protein phosphatase PP1, putative 291
L. major   LmjF.32.1020   OG5_154653   protein kinase, putative 291
L. major   LmjF.16.1200   OG5_148443   cyclophilin 13, putative 291
L. major   LmjF.08.0510   OG5_147625   ribose-phosphate pyrophosphokinase, putative 291
L. major   LmjF.30.0380   OG5_136796   phosphatase 2C, putative 291
L. major   LmjF.25.0750   OG5_150267   protein phosphatase, putative 291
L. major   LmjF.16.0550   OG5_126793   orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative, ... 291
L. major   LmjF.15.0170   OG5_142545   protein phosphatase 2C, putative 291
L. major   LmjF.28.1970   OG5_129695   ribose 5-phosphate isomerase, putative 291
L. major   LmjF.04.0450   OG5_135138   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2 ... 291
L. major   LmjF.22.1450   OG5_141132   cyclophilin 6, putative 291
L. major   LmjF.03.0910   OG5_128875   inorganic pyrophosphatase, putative 291
L. major   LmjF.29.2670   OG5_150111   serine/threonine-protein kinase Nek3, putative,protein kinase, putative 291
L. major   LmjF.28.3000   OG5_148164   protein kinase, putative 291
L. major   LmjF.30.2770   OG5_148158   superoxide dismutase, putative 291
L. major   LmjF.29.2490   OG5_154473   protein kinase, putative 291
L. major   LmjF.31.3160   OG5_139463   protein kinase, putative 291
L. major   LmjF.34.0130   OG5_150839   malate dehydrogenase, putative 291
L. major   LmjF.31.0840   OG5_127315   lipase precursor-like protein 291
L. major   LmjF.01.0220   OG5_133785   cyclophilin 12, putative 291
L. major   LmjF.02.0360   OG5_143898   casein kinase II, alpha chain, putative 291
L. major   LmjF.01.0500   OG5_126601   fatty acyl CoA synthetase 2, putative 291
L. major   LmjF.08.0100   OG5_141243   dual-specificity protein phosphatase, putative 291

Showing page 4 (records 76-100) of 330