Target list

Search results for query: PLoS NTD Query 2 (L. major)

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  • Score for genes in query #95 (Mtb enz (EC + func. Categ.) (now searched on lma)): 100
  • Score for genes in query #99 (Mtb PDB (now searched on lma)): 50
  • Score for genes in query #96 (Mtb Pubmed (now searched on lma)): 35
  • Score for genes in query #98 (Mtb no TM domain (now searched on lma)): 20
  • Score for genes in query #104 (Mtb dindex >=0.6 (now searched on lma)): 35
  • Score for genes in query #105 (Mtb Compd desirability >0.3 (now searched on lma)): 35
  • Score for genes in query #102 (Mtb any genetic validation (now searched on lma)): 50
  • Score for genes in query #110 (Lma in Tbr and Tcr): 25
  • Score for genes in query #101 (Mtb not in humans (now searched on lma)): 25
  • Score for genes in query #100 (Mtb modbase (now searched on lma)): 30
  • Score for genes in query #97 (Mtb mwt <100kDa (now searched on lma)): 20
  • Score for genes in query #106 (Mtb assayable (now searched on lma)): 35
  • Score for genes in query #107 (Mtb all proteins (now searched on lma)): 1

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8243 records found | Showing page 3 of 330 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.30.3110   OG5_128279   S-adenosylmethionine decarboxylase 301
L. major   LmjF.30.3520   OG5_126734   S-adenosylmethionine synthetase 301
L. major   LmjF.21.0240   OG5_126743   hexokinase, putative 301
L. major   LmjF.28.2860   OG5_127410   cytosolic malate dehydrogenase 301
L. major   LmjF.22.1360   OG5_127590   farnesyl pyrophosphate synthase 301
L. major   LmjF.29.2360   OG5_128020   aspartyl aminopeptidase, putative,metallo-peptidase, Clan MH, Family M20 301
L. major   LmjF.09.0410   OG5_126990   protein kinase, putative 301
L. major   LmjF.18.1080   OG5_126748   protein kinase A catalytic subunit 301
L. major   LmjF.26.0300   OG5_127177   aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 301
L. major   LmjF.31.2940   OG5_129470   squalene synthase, putative 301
L. major   LmjF.28.1780   OG5_129147   DNA topoisomerase III, putative 301
L. major   LmjF.28.0690   OG5_126821   serine/threonine protein phosphatase catalytic subunit, putative 301
L. major   LmjF.06.0370   OG5_127569   glutamine synthetase, putative 301
L. major   LmjF.28.2430   OG5_127061   vacuolar ATP synthase subunit b, putative 301
L. major   LmjF.07.1030   OG5_128367   peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 301
L. major   LmjF.19.1530   OG5_126727   peptidylprolyl isomerase-like protein 301
L. major   LmjF.29.2020   OG5_126655   serine/threonine protein kinase, putative,protein kinase, putative 301
L. major   LmjF.26.2530   OG5_127131   serine/threonine protein phosphatase, putative 301
L. major   LmjF.11.1100   OG5_129288   lanosterol 14-alpha-demethylase, putative 301
L. major   LmjF.09.0400   OG5_126990   protein kinase, putative 301
L. major   LmjF.21.1210   OG5_129576   thymidine kinase, putative 301
L. major   LmjF.34.0110   OG5_126762   adenylate kinase, putative 301
L. major   LmjF.13.1190   OG5_127011   adenylosuccinate synthetase, putative 301
L. major   LmjF.20.0110   OG5_126776   phosphoglycerate kinase B, cytosolic 301
L. major   LmjF.36.3130   OG5_140933   cyclophilin 10, putative 291

Showing page 3 (records 51-75) of 330