Target list

Search results for query: PLoS NTD query (L. major)

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  • Score for genes in query #530 (L. major conserved in TriTryps): 25
  • Score for genes in query #532 (L. major druggability >=0.6): 35
  • Score for genes in query #531 (L. major genetic validation): 50
  • Score for genes in query #524 (L. major PubMed publications): 35
  • Score for genes in query #534 (L. major assayability precedent): 35
  • Score for genes in query #527 (L. major PDB structures): 50
  • Score for genes in query #526 (L. major no transmembrane domains): 20
  • Score for genes in query #525 (L. major MW < 100 kD): 20
  • Score for genes in query #522 (all L. major proteins): 1
  • Score for genes in query #528 (L. major ModBase models): 30
  • Score for genes in query #523 (L. major enzymes): 100
  • Score for genes in query #529 (L. major not in humans): 25

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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8243 records found | Showing page 6 of 330 (records 126-150) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.20.0100   OG5_126776   phosphoglycerate kinase C, glycosomal 281
L. major   LmjF.33.1690   OG5_127429   DNA polymerase delta catalytic subunit, putative 281
L. major   LmjF.34.3440   OG5_127702   DNA topoisomerase IB, large subunit 281
L. major   LmjF.16.0530   OG5_127289   dihydroorotate dehydrogenase 281
L. major   LmjF.18.0090   OG5_126880   alpha glucosidase II subunit, putative 281
L. major   LmjF.31.0560   OG5_128331   mevalonate kinase, putative 281
L. major   LmjF.18.0480   OG5_127417   uracil-DNA-glycosylase, putative 281
L. major   LmjF.32.0700   OG5_128230   ubiquitin carrier protein 4, putative 281
L. major   LmjF.30.2980   OG5_126628   glyceraldehyde 3-phosphate dehydrogenase, glycosomal 281
L. major   LmjF.13.0390   OG5_126605   alpha tubulin 281
L. major   LmjF.21.1080   OG5_126712   cell division protein kinase 2,cdc2-related kinase 281
L. major   LmjF.24.2060   OG5_126720   transketolase 281
L. major   LmjF.19.1440   OG5_126781   mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 281
L. major   LmjF.36.5370   OG5_128637   tyrosine specific protein phosphatase, putative 281
L. major   LmjF.18.0200   OG5_133772   UDP-galactopyranose mutase 281
L. major   LmjF.16.1540   OG5_128177   DNA polymerase I alpha catalytic subunit, putative 281
L. major   LmjF.34.0150   OG5_126911   malate dehydrogenase, putative 276
L. major   LmjF.12.0280   OG5_126750   ornithine decarboxylase, putative 276
L. major   LmjF.34.4330   OG5_131023   quinonoid dihydropteridine reductase 276
L. major   LmjF.26.0660   OG5_127741   protein disulfide isomerase, putative 271
L. major   LmjF.18.0880   OG5_139903   cyclosporin 16, putative 271
L. major   LmjF.20.1180   OG5_135138   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2 ... 271
L. major   LmjF.15.1290   OG5_128755   mitochondrial DNA topoisomerase II 271
L. major   LmjF.17.0200   OG5_126617   receptor-type adenylate cyclase a 271
L. major   LmjF.31.2460   OG5_127315   lipase, putative 271

Showing page 6 (records 126-150) of 330