Target list

Search results for query: PLoS NTD query (L. major)

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  • Score for genes in query #524 (L. major PubMed publications): 35
  • Score for genes in query #528 (L. major ModBase models): 30
  • Score for genes in query #529 (L. major not in humans): 25
  • Score for genes in query #532 (L. major druggability >=0.6): 35
  • Score for genes in query #530 (L. major conserved in TriTryps): 25
  • Score for genes in query #526 (L. major no transmembrane domains): 20
  • Score for genes in query #531 (L. major genetic validation): 50
  • Score for genes in query #534 (L. major assayability precedent): 35
  • Score for genes in query #525 (L. major MW < 100 kD): 20
  • Score for genes in query #523 (L. major enzymes): 100
  • Score for genes in query #522 (all L. major proteins): 1
  • Score for genes in query #527 (L. major PDB structures): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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8243 records found | Showing page 5 of 330 (records 101-125) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.34.0800   OG5_204249   serine/threonine-protein phosphatase PP1, putative 291
L. major   LmjF.29.1960   OG5_128140   fumarate hydratase, putative 291
L. major   LmjF.30.0020   OG5_148842   cyclophilin 9, putative 291
L. major   LmjF.31.0830   OG5_236284   lipase, putative;with=GeneDB:LinJ31_V3.0860 291
L. major   LmjF.34.0780   OG5_204150   serine/threonine-protein phosphatase PP1, putative 291
L. major   LmjF.19.0710   OG5_127145   glycosomal malate dehydrogenase 291
L. major   LmjF.31.0050   OG5_147567   cyclophilin 5, putative 291
L. major   LmjF.36.1520   OG5_135887   hypothetical protein, conserved,nima-related protein kinase, putative 291
L. major   LmjF.17.0140   OG5_134039   peptidase t, putative,peptidase T, putative, metallo-peptidase, ClanMH, family M ... 291
L. major   LmjF.14.0900   OG5_141696   protein phosphatase 2C-like protein 291
L. major   LmjF.01.0470   OG5_126601   fatty acyl CoA syntetase 1, putative 291
L. major   LmjF.31.2630   OG5_140695   serine/threonine protein phosphatase pp1(5.9), putative 291
L. major   LmjF.34.0790   OG5_183497   serine/threonine-protein phosphatase PP1, putative 291
L. major   LmjF.36.6650   OG5_129051   2,3-bisphosphoglycerate-independent phosphoglycerate mutase 291
L. major   LmjF.36.2050   OG5_151863   serine/threonine protein phosphatase, putative 291
L. major   LmjF.27.1810   OG5_128435   glycosomal phosphoenolpyruvate carboxykinase, putative 291
L. major   LmjF.34.0850   OG5_152628   serine/threonine-protein phosphatase PP1, putative 291
L. major   LmjF.24.1315   OG5_148681   cyclophilin 8, putative 291
L. major   LmjF.16.0540   OG5_128535   aspartate carbamoyltransferase, putative 291
L. major   LmjF.28.2220   OG5_131753   2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like 291
L. major   LmjF.34.0120   OG5_154462   adenylate kinase 2 291
L. major   LmjF.32.0080   OG5_127597   N-myristoyl transferase, putative 281
L. major   LmjF.28.2280   OG5_127113   DNA topoisomerase ii 281
L. major   LmjF.26.0210   OG5_127826   silent information regulator 2, putative 281
L. major   LmjF.23.0110   OG5_127109   GDP-mannose pyrophosphorylase 281

Showing page 5 (records 101-125) of 330