Target list

Search results for query: Weighted list for comparison of PLOS-NTD vs. this prioritization

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #13 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #1 (Sma EC numbers - uploaded list): 10
  • Score for genes in query #34 (top-25 of ranked list for PLOS-NTD; Posted List 336, No tissue-differential gene expression data): 0
  • Score for genes in query #31 (top-100 of ranked list for PLOS-NTD; Posted List 336, No tissue-differential gene expression data): 0
  • Score for genes in query #15 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #8 (Sterility in C. elegans): 3
  • Score for genes in query #7 (Morphology Defect in C. elegans): 3
  • Score for genes in query #19 (Sma uploaded list of targets identified by STARlite search (Berriman et al, 2009)): 10
  • Score for genes in query #26 (S. mansoni orthologs of C. elegans genes differentially expressed in neurons): 10
  • Score for genes in query #6 (Larval/Adult Lethal/Arrest in C. elegans): 10
  • Score for genes in query #4 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #9 (any essentiality evidence): 3
  • Score for genes in query #5 (Growth Defect in C. elegans): 3
  • Score for genes in query #2 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #14 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #10 (structural model available): 10
  • Score for genes in query #12 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #24 (S. mansoni orthologs of C. elegans genes differentially expressed in muscle): 10
  • Score for genes in query #17 (Sma in Cel): 10
  • Score for genes in query #20 (Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)): 10
  • Score for genes in query #11 (druggable genes inferred by sequence simiarity): 10
  • Score for genes in query #3 (Orthologs of D. melanogaster genes with mutant phenotype neurophysiological defect): 10
  • Score for genes in query #16 (Sma all proteins): 1
  • Score for genes in query #18 (Sma uploaded list of metabolic chokepoint enzymes (Berriman et al, 2009)): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

12680 records found | Showing page 507 of 508 (records 12651-12675) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_068060.1   OG5_129521   serine/threonine protein kinase 1
S. mansoni   Smp_022450.1   OG5_185016   hypothetical protein 1
S. mansoni   Smp_196000     No group hypothetical protein 1
S. mansoni   Smp_196010     No group stomatin-related 1
S. mansoni   Smp_066670.1   OG5_165402   syntaxin 1
S. mansoni   Smp_064800.3   OG5_172723   hypothetical protein 1
S. mansoni   Smp_087940.1     No group gaba(A) receptor-associated protein 1
S. mansoni   Smp_159500   OG5_126814   hypothetical protein 1
S. mansoni   Smp_002600.2   OG5_130246   lysosomal Pro-Xaa carboxypeptidase (S28 family) 1
S. mansoni   Smp_139580   OG5_206262   hypothetical protein 1
S. mansoni   Smp_195090     No group hypothetical protein 1
S. mansoni   Smp_042280.2   OG5_129956   hypothetical protein 1
S. mansoni   Smp_109150   OG5_127305   hypothetical protein 1
S. mansoni   Smp_022570.1   OG5_132240   ATXN7L3-like protein 1
S. mansoni   Smp_125320     No group hypothetical protein 1
S. mansoni   Smp_052800.1   OG5_196040   poly(p)/ATP NAD kinase 1
S. mansoni   Smp_084180.2   OG5_185020   ribonucleoprotein A1b 1
S. mansoni   Smp_058530.2   OG5_167642   hypothetical protein 1
S. mansoni   Smp_122630     No group hypothetical protein 1
S. mansoni   Smp_122760.6   OG5_154841   hypothetical protein 1
S. mansoni   Smp_190410   OG5_126670   hypothetical protein 1
S. mansoni   Smp_097020.2   OG5_127678   fbxl20 1
S. mansoni   Smp_196040     No group shc transforming protein 1
S. mansoni   Smp_129950.1   OG5_169527   rna-binding protein 12 (sh3/ww domain anchor protein in the nucleus) (swan) 1
S. mansoni   Smp_039180.2   OG5_128565   nuclear protein localization 1

Showing page 507 (records 12651-12675) of 508