Target list

Search results for query: Weighted list for comparison of PLOS-NTD vs. this prioritization

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #7 (Morphology Defect in C. elegans): 3
  • Score for genes in query #2 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #19 (Sma uploaded list of targets identified by STARlite search (Berriman et al, 2009)): 10
  • Score for genes in query #12 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #34 (top-25 of ranked list for PLOS-NTD; Posted List 336, No tissue-differential gene expression data): 0
  • Score for genes in query #16 (Sma all proteins): 1
  • Score for genes in query #18 (Sma uploaded list of metabolic chokepoint enzymes (Berriman et al, 2009)): 10
  • Score for genes in query #15 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #14 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #24 (S. mansoni orthologs of C. elegans genes differentially expressed in muscle): 10
  • Score for genes in query #31 (top-100 of ranked list for PLOS-NTD; Posted List 336, No tissue-differential gene expression data): 0
  • Score for genes in query #10 (structural model available): 10
  • Score for genes in query #9 (any essentiality evidence): 3
  • Score for genes in query #20 (Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)): 10
  • Score for genes in query #13 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #8 (Sterility in C. elegans): 3
  • Score for genes in query #11 (druggable genes inferred by sequence simiarity): 10
  • Score for genes in query #17 (Sma in Cel): 10
  • Score for genes in query #4 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #1 (Sma EC numbers - uploaded list): 10
  • Score for genes in query #5 (Growth Defect in C. elegans): 3
  • Score for genes in query #3 (Orthologs of D. melanogaster genes with mutant phenotype neurophysiological defect): 10
  • Score for genes in query #26 (S. mansoni orthologs of C. elegans genes differentially expressed in neurons): 10
  • Score for genes in query #6 (Larval/Adult Lethal/Arrest in C. elegans): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

12680 records found | Showing page 508 of 508 (records 12676-12680) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_184700.1   OG5_131411   hypothetical protein 1
S. mansoni   Smp_062260.3   OG5_126624   uridine cytidine kinase I 1
S. mansoni   Smp_171090.1   OG5_246884   hypothetical protein 1
S. mansoni   Smp_149480   OG5_131844   hypothetical protein 1
S. mansoni   Smp_195080     No group cofilin 1

Showing page 508 (records 12676-12680) of 508