Target list

Search results for query: top-100 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data

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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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98 records found | Showing page 2 of 4 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
B. malayi   Bm1_55200   OG5_127100   Proteasome A-type and B-type family protein
B. malayi   Bm1_20715   OG5_126605   tubulin alpha-2 chain
B. malayi   Bm1_28835   OG5_128511   Transcription initiation factor IIA, gamma subunit, helical domain containing pr ...
B. malayi   Bm1_51640   OG5_127762   Proteasome A-type and B-type family protein
B. malayi   Bm1_30555   OG5_127705   Proteasome A-type and B-type family protein
B. malayi   Bm1_32860   OG5_126723   Valyl-tRNA synthetase
B. malayi   Bm1_32455   OG5_127555   mannose-6-phosphate isomerase, class I family protein
B. malayi   Bm1_12875   OG5_126821   Serine/threonine protein phosphatase PP1-beta catalytic subunit
B. malayi   Bm1_39900   OG5_131257   Sex muscle abnormal protein 5
B. malayi   Bm1_56235   OG5_126971   Ras-related protein Rab-11B
B. malayi   Bm1_54155   OG5_126745   Probable dimethyladenosine transferase
B. malayi   Bm1_39760   OG5_126677   seryl-tRNA synthetase, mitochondrial precursor, putative
B. malayi   Bm1_31220   OG5_126758   phosphofructokinase
B. malayi   Bm1_31540   OG5_126779   2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor
B. malayi   Bm1_55955   OG5_129885   GTP-binding protein
B. malayi   Bm1_55385   OG5_127261   40S ribosomal protein S12
B. malayi   Bm1_14125   OG5_127834   proteasome subunit beta type 1
B. malayi   Bm1_12165   OG5_127626   methionyl-tRNA synthetase
B. malayi   Bm1_38680   OG5_126605   tubulin alpha chain - mouse
B. malayi   Bm1_49370   OG5_131020   Protein kinase domain containing protein
B. malayi   Bm1_01930   OG5_126758   6-phosphofructokinase
B. malayi   Bm1_20815   OG5_132787   integrin-linked kinase
B. malayi   Bm1_25205   OG5_127407   leucyl-tRNA synthetase
B. malayi   Bm1_44575   OG5_127113   DNA gyrase/topoisomerase IV, A subunit family protein
B. malayi   Bm1_34670   OG5_129541   Plus-3 domain containing protein