Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
6741 records found | Showing page 6 of 270 (records 126-150) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| T. cruzi | TcCLB.476421.9 | OG5_197818 | STE/STE11 serine/threonine-protein kinase, putative |
| T. cruzi | TcCLB.476733.29 | No group | serine-threonine dehydratase, putative |
| T. cruzi | TcCLB.477079.10 | OG5_134553 | protein kinase, putative |
| T. cruzi | TcCLB.478671.9 | OG5_128065 | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative |
| T. cruzi | TcCLB.480561.10 | OG5_126562 | trans-sialidase, putative |
| T. cruzi | TcCLB.480653.10 | OG5_145839 | hypothetical protein, conserved |
| T. cruzi | TcCLB.480785.10 | OG5_149101 | serine/threonine kinase, putative |
| T. cruzi | TcCLB.481435.9 | OG5_127480 | clathrin heavy chain, putative |
| T. cruzi | TcCLB.482369.10 | OG5_148170 | protein phosphatase 2A regulatory subunit, putative |
| T. cruzi | TcCLB.483009.9 | OG5_130856 | exonuclease, putative |
| T. cruzi | TcCLB.484299.10 | No group | trypanothione reductase, putative |
| T. cruzi | TcCLB.484299.4 | OG5_128272 | ATP-dependent DEAD/H RNA helicase, putative |
| T. cruzi | TcCLB.486901.10 | OG5_132941 | endonuclease/exonuclease/phosphatase, putative |
| T. cruzi | TcCLB.494675.10 | OG5_126601 | fatty acyl CoA synthetase 2, putative |
| T. cruzi | TcCLB.495369.10 | OG5_142984 | glyoxalase II |
| T. cruzi | TcCLB.498829.21 | OG5_152016 | hypothetical protein |
| T. cruzi | TcCLB.503395.30 | OG5_131289 | Uncharacterized ACR, COG1678, putative |
| T. cruzi | TcCLB.503395.40 | OG5_127236 | 60S ribosomal protein L18, putative |
| T. cruzi | TcCLB.503399.10 | OG5_144579 | hypothetical protein, conserved |
| T. cruzi | TcCLB.503399.20 | OG5_130792 | hydrolase, alpha/beta fold family, putative |
| T. cruzi | TcCLB.503399.29 | OG5_146696 | hydrolase-like protein |
| T. cruzi | TcCLB.503401.40 | OG5_176170 | glycosyl transferase, putative |
| T. cruzi | TcCLB.503403.20 | OG5_126562 | trans-sialidase, Group II, putative |
| T. cruzi | TcCLB.503405.10 | OG5_127569 | glutamine synthetase, putative |
| T. cruzi | TcCLB.503407.20 | OG5_140391 | SUMO1/Ulp2, putative |