Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
179 records found | Showing page 1 of 8 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| P. falciparum | PF3D7_0104400 | OG5_130373 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase |
| P. falciparum | PF3D7_0109800 | OG5_127036 | phenylalanine--tRNA ligase alpha subunit |
| P. falciparum | PF3D7_0202700 | OG5_126937 | octaprenyl pyrophosphate synthase |
| P. falciparum | PF3D7_0203000 | OG5_126585 | repetitive organellar protein, putative |
| P. falciparum | PF3D7_0204900 | OG5_127211 | ubiE/COQ5 methyltransferase, putative |
| P. falciparum | PF3D7_0206700 | OG5_130883 | adenylosuccinate lyase |
| P. falciparum | PF3D7_0207200 | OG5_127463 | iron-sulfur assembly protein, putative |
| P. falciparum | PF3D7_0208500 | OG5_127028 | acyl carrier protein |
| P. falciparum | PF3D7_0209300 | OG5_130616 | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| P. falciparum | PF3D7_0211400 | OG5_129509 | beta-ketoacyl-ACP synthase III |
| P. falciparum | PF3D7_0211800 | OG5_126756 | asparagine--tRNA ligase |
| P. falciparum | PF3D7_0212200 | OG5_126884 | mitochondrial ribosomal protein L12 precursor, putative |
| P. falciparum | PF3D7_0214200 | OG5_127268 | mitochondrial ribosomal protein L13 precursor, putative |
| P. falciparum | PF3D7_0216700 | OG5_126585 | autophagy-related protein 11, putative |
| P. falciparum | PF3D7_0303700 | OG5_128117 | lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogen ... |
| P. falciparum | PF3D7_0305000 | OG5_127934 | elongation factor Ts |
| P. falciparum | PF3D7_0318200 | OG5_126637 | DNA-directed RNA polymerase II subunit RPB1 |
| P. falciparum | PF3D7_0412100 | OG5_127680 | mitochondrial ribosomal protein S12 precursor, putative |
| P. falciparum | PF3D7_0417200 | OG5_127385 | bifunctional dihydrofolate reductase-thymidylate synthase |
| P. falciparum | PF3D7_0420200 | OG5_130884 | holo-[acyl-carrier-protein] synthase, putative |
| P. falciparum | PF3D7_0500800 | OG5_126585 | mature parasite-infected erythrocyte surface antigen |
| P. falciparum | PF3D7_0503000 | OG5_130709 | 50S ribosomal protein L28, apicoplast, putative |
| P. falciparum | PF3D7_0503100 | OG5_130885 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, putative |
| P. falciparum | PF3D7_0508800 | OG5_127389 | single-stranded DNA-binding protein |
| P. falciparum | PF3D7_0509600 | OG5_126756 | asparagine--tRNA ligase |